Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.62 |
| ▸ | CNR1 | P21554 | 3/20 | 0.62 |
| ▸ | CNR2 | P34972 | 2/20 | 0.57 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.57 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.57 |
| ▸ | PLCD1 | P51178 | 1/20 | 0.54 |
| ▸ | F2 | P00734 | 1/20 | 0.53 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.53 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.53 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.53 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.53 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.52 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.52 |
| ▸ | FGF1 | P05230 | 1/20 | 0.52 |
| ▸ | FGF2 | P09038 | 1/20 | 0.52 |
| ▸ | VEGFA | P15692 | 1/20 | 0.52 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21361159 | 0.87 | TDP1 (0.55) | TDP1CNR1CNR2FOLH1F2 | |
| SCHEMBL21361157 | 0.86 | TDP1 (0.61) | TDP1CNR1CNR2FOLH1CAPN1 | |
| SCHEMBL21958835 | 0.86 | TDP1 (0.70) | TDP1CNR1CNR2FOLH1CAPN1 | |
| SCHEMBL18779801 | 0.85 | TDP1 (0.78) | TDP1FOLH1CAPN1PLCD1F2 | |
| SCHEMBL15353873 | 0.85 | TDP1 (0.60) | TDP1CNR1FOLH1CAPN1F2 | |
| SCHEMBL23567351 | 0.85 | TDP1 (0.67) | TDP1CNR1CNR2FOLH1CAPN1 | |
| SCHEMBL2768198 | 0.85 | TDP1 (0.81) | TDP1CNR1CNR2FOLH1CAPN1 | |
| SCHEMBL18257192 | 0.85 | TDP1 (0.81) | TDP1CNR1CNR2FOLH1CAPN1 | |
| SCHEMBL19959667 | 0.85 | TDP1 (0.81) | TDP1CNR1CNR2FOLH1CAPN1 | |
| SCHEMBL9807479 | 0.84 | TDP1 (0.77) | TDP1CNR1FOLH1CAPN1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10413621-B2 | Composition and methods for imaging cells | CASE WESTERN RESERVE UNIVERSITY (US) | 2019-09-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10413621-B2 | Composition and methods for imaging cells | MCL1, TP53, HNRNPAB | TDP1 3017/4885CNR1 2138/4885CNR2 2381/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.