Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.67 |
| ▸ | CNR1 | P21554 | 3/20 | 0.61 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.60 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.57 |
| ▸ | PLCD1 | P51178 | 1/20 | 0.57 |
| ▸ | F2 | P00734 | 1/20 | 0.56 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.56 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.56 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.56 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.56 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.55 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | ABL1 | P00519 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | IDE | P14735 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21958835 | 0.91 | TDP1 (0.70) | TDP1CNR1CAPN1FOLH1PLCD1 | |
| SCHEMBL18779801 | 0.89 | TDP1 (0.78) | TDP1CAPN1FOLH1PLCD1F2 | |
| SCHEMBL14570855 | 0.88 | TDP1 (0.74) | TDP1CNR1CAPN1FOLH1PLCD1 | |
| SCHEMBL17385530 | 0.87 | TDP1 (0.68) | TDP1CNR1CAPN1FOLH1PLCD1 | |
| SCHEMBL21140191 | 0.87 | TDP1 (0.70) | TDP1CNR1CAPN1FOLH1PLCD1 | |
| SCHEMBL14523052 | 0.87 | TDP1 (0.70) | TDP1CNR1CAPN1FOLH1PLCD1 | |
| SCHEMBL24067575 | 0.87 | TDP1 (0.76) | TDP1CNR1CAPN1FOLH1PLCD1 | |
| SCHEMBL23871921 | 0.86 | TDP1 (0.67) | TDP1CNR1CAPN1FOLH1PLCD1 | |
| SCHEMBL21140233 | 0.86 | TDP1 (0.69) | TDP1CNR1CAPN1FOLH1PLCD1 | |
| SCHEMBL2768198 | 0.86 | TDP1 (0.81) | TDP1CNR1CAPN1FOLH1PLCD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11161884-B2 | Modified biotin, streptavidin mutant, and usage of them | SAVID THERAPEUTICS INC. (JP) | 2021-11-02 | — | — | US | disclosed |
| US-11124549-B2 | — | — | 2021-09-21 | — | — | US | disclosed |
| EP-3842440-A2 | MODIFIED BIOTIN, STREPTAVIDIN MUTANT, AND USAGE OF THEM | Savid Therapeutics Inc. (JP) | 2021-06-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11124549-B2 | — | BTD, HLCS, BROX | TDP1 4590/4885CNR1 4634/4885CAPN1 4713/4885 |
| US-11161884-B2 | Modified biotin, streptavidin mutant, and usage of them | BTD, HLCS, BROX | TDP1 4670/4885CNR1 4590/4885CAPN1 4665/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.