Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 13/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | CCR8 | P51685 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22859737 | 0.89 | KCNH2 (0.38) | CD274KCNH2CCR8GRIN2BGRM4 | |
| SCHEMBL21361250 | 0.84 | MAOB (0.38) | GRM4TLR7NPC1 | |
| SCHEMBL24120312 | 0.83 | KCNH2 (0.40) | CD274KCNH2GRIN2BGRM4TLR7 | |
| SCHEMBL21361259 | 0.79 | CCR8 (0.47) | KCNH2CCR8MAPT | |
| SCHEMBL24120381 | 0.78 | MAOB (0.39) | KCNH2GRIN2BGRM4TLR7NPC1 | |
| SCHEMBL22859732 | 0.76 | SLC6A9 (0.34) | POLBMAPT | |
| SCHEMBL21361231 | 0.76 | TNKS2 (0.36) | KCNH2GRIN2BGRM4NPC1 | |
| SCHEMBL24120382 | 0.75 | GRM4 (0.38) | CD274KCNH2GRIN2BGRM4TLR7 | |
| SCHEMBL24120432 | 0.74 | RBP4 (0.41) | KCNH2CCR8GRIN2BGRM4MAPT | |
| SCHEMBL21361306 | 0.74 | GAA (0.44) | KCNH2CCR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019175117-A1 | SPIRO CYCLOHEXANEDIONE DERIVATES AS HERBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2019-09-19 | — | — | WO | disclosed |