SCHEMBL21361278

SCHEMBL21361278

COC1=C(c2c(C)cc(Br)cc2C)C(=O)CC2(CCN(C=O)CC2)C1

nearest known ligand 0.34

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24426556 0.85
SCHEMBL26034682 0.81
SCHEMBL21357431 0.80 GPR119 (0.40)
SCHEMBL24426524 0.74 GRM5 (0.30)
SCHEMBL24426506 0.73
SCHEMBL21357789 0.72
SCHEMBL24426514 0.71
SCHEMBL24426591 0.71
SCHEMBL24092256 0.70 CYP2D6 (0.34)
SCHEMBL21361211 0.69 ACACB (0.39)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3765445-B1 SPIRO CYCLOHEXANEDIONE DERIVATES AS HERBICIDES SYNGENTA PARTICIPATIONS AG (CH) 2023-08-30 EP disclosed
WO-2019175117-A1 SPIRO CYCLOHEXANEDIONE DERIVATES AS HERBICIDES SYNGENTA PARTICIPATIONS AG (CH) 2019-09-19 WO disclosed