Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 5/20 | 0.39 |
| ▸ | GPR183 | P32249 | 1/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | CTSD | P07339 | 1/20 | 0.34 |
| ▸ | CTSE | P14091 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | SPR | P35270 | 2/20 | 0.34 |
| ▸ | NAMPT | P43490 | 4/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
| ▸ | PRKDC | P78527 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21357431 | 0.90 | GPR119 (0.40) | ACACBGPR183GPR119KDM4EMAPT | |
| SCHEMBL22345592 | 0.86 | GPR183 (0.41) | ACACBGPR183GPR119SCD5HDAC1 | |
| SCHEMBL21357462 | 0.84 | USP30 (0.37) | ACACBGPR183GPR119SCD5HDAC1 | |
| SCHEMBL21361210 | 0.83 | ACACB (0.35) | ACACBGPR183GPR119SCD5HDAC1 | |
| SCHEMBL21357443 | 0.82 | ACACB (0.40) | ACACBGPR119SCD5HDAC1HDAC2 | |
| SCHEMBL21344870 | 0.78 | GPR183 (0.39) | ACACBGPR183GPR119HDAC1HDAC2 | |
| SCHEMBL22907827 | 0.76 | GPR183 (0.33) | ACACBGPR183 | |
| SCHEMBL24092256 | 0.72 | CYP2D6 (0.34) | THRB | |
| SCHEMBL904136 | 0.70 | USP2 (0.49) | ACACBGPR183GPR119KDM4EMAPT | |
| SCHEMBL24426494 | 0.69 | ALDH1A1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3765445-B1 | SPIRO CYCLOHEXANEDIONE DERIVATES AS HERBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2023-08-30 | — | — | EP | disclosed |
| WO-2019175117-A1 | SPIRO CYCLOHEXANEDIONE DERIVATES AS HERBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2019-09-19 | — | — | WO | disclosed |