SCHEMBL2136144

SCHEMBL2136144

C[Zr](C)C1C=Cc2ccccc21

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 2/20 0.38
HTR6 P50406 1/20 0.37
KDM4E B2RXH2 2/20 0.34
CYP2D6 P10635 2/20 0.34
BRD4 O60885 1/20 0.34
CCL2 P13500 1/20 0.34
LMNA P02545 1/20 0.34
TP53 P04637 1/20 0.34
CHRM2 P08172 1/20 0.34
CYP3A4 P08684 1/20 0.34
CHRM1 P11229 1/20 0.34
DRD2 P14416 1/20 0.34
ADRA2B P18089 1/20 0.34
ADRA2C P18825 1/20 0.34
NFKB1 P19838 1/20 0.34
CHRM3 P20309 1/20 0.34
SLC6A2 P23975 1/20 0.34
HTR2C P28335 1/20 0.34
ADRA1A P35348 1/20 0.34
HRH1 P35367 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29758162 1.00 HTR2A (0.38) HTR2AHTR6KDM4ECYP2D6BRD4
SCHEMBL6763868 0.87 HTR2A (0.38) HTR2AHTR6KDM4ECYP2D6BRD4
SCHEMBL15863401 0.82 HTR2A (0.40) HTR2AHTR6KDM4ECYP2D6BRD4
SCHEMBL5183638 0.80 HTR2A (0.39) HTR2AHTR6KDM4ECYP2D6BRD4
SCHEMBL4925283 0.78 HTR2A (0.38) HTR2AHTR6KDM4ECYP2D6BRD4
SCHEMBL812667 0.78 HTR2A (0.38) HTR2AHTR6KDM4ECYP2D6BRD4
SCHEMBL6440197 0.78 HTR2A (0.38) HTR2AHTR6KDM4ECYP2D6BRD4
SCHEMBL5278165 0.78 HTR2A (0.38) HTR2AHTR6KDM4ECYP2D6BRD4
SCHEMBL3798506 0.78 HTR2A (0.38) HTR2AHTR6KDM4ECYP2D6BRD4
SCHEMBL7800583 0.78 MEN1 (0.34) MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1738678-A Alkene tandem type tetramer-polymerization method SASOL TECH PTY LTD (ZA) 2006-02-22 CN claimed
CN-113999334-B Catalyst for olefin polymerization and preparation method and application thereof 上海化工研究院有限公司 2023-08-29 CN disclosed
CN-113999334-A Catalyst for olefin polymerization and preparation method and application thereof 上海化工研究院有限公司 2022-02-01 CN disclosed
CN-109879998-A Preparation method for producing polyethylene elastomer by gas-phase fluidized bed process 中国石油天然气股份有限公司 2019-06-14 CN disclosed
CN-102796218-A Metallocene catalyst for producing low gel polyethylene, and preparation method and application thereof SHANGHAI RES INST CHEMICAL IND 2012-11-28 CN disclosed
EP-2443160-A1 OLIGOMERIZATION OF ALPHA OLEFINS USING METALLOCENE-SSA CATALYST SYSTEMS AND USE OF THE RESULTANT POLYALPHAOLEFINS TO PREPARE LUBRICANT BLENDS Chevron Phillips Chemical Company LP (US) 2012-04-25 EP disclosed
EP-2064248-A1 PREPARATION OF POLYMERIZATION CATALYST ACTIVATORS UTILIZING INDOLE-MODIFIED SILICA SUPPORTS ExxonMobil Chemical Patents Inc. (US) 2009-06-03 EP disclosed
WO-2008027116-A1 PREPARATION OF POLYMERIZATION CATALYST ACTIVATORS UTILIZING INDOLE-MODIFIED SILICA SUPPORTS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2008-03-06 WO disclosed
EP-0889089-B2 PROPYLENE POLYMER COMPOSITION AND THERMOFORMED OBJECT MITSUI CHEMICALS INC (JP) 2007-12-05 EP disclosed
EP-1709085-A2 SUPPORTED ACTIVATOR ExxonMobil Chemical Patents, Inc., A Corporation of the State of Delaware (US) 2006-10-11 EP disclosed
CN-1738678-A Alkene tandem type tetramer-polymerization method SASOL TECH PTY LTD (ZA) 2006-02-22 CN disclosed
WO-2005068515-A2 SUPPORTED ACTIVATOR FOR POLYMERISATION EXXONMOBIL CHEMICAL PATENTS, INC. (US) 2005-07-28 WO disclosed
EP-0889089-B1 PROPYLENE POLYMER COMPOSITION AND THERMOFORMED OBJECT MITSUI CHEMICALS INC (JP) 2003-08-13 EP disclosed
EP-0889089-A1 PROPYLENE POLYMER COMPOSITION AND THERMOFORMED OBJECT Mitsui Chemicals, Inc. (JP) 1999-01-07 EP disclosed
CN-1182095-A Ethylene-alpha-olefin copolymer MITSUBISHI CHEM CORP (JP) 1998-05-20 CN disclosed