SCHEMBL29758162

SCHEMBL29758162

C[Zr](C)C1C=Cc2ccccc21

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 2/20 0.38
HTR6 P50406 1/20 0.37
KDM4E B2RXH2 2/20 0.34
CYP2D6 P10635 2/20 0.34
BRD4 O60885 1/20 0.34
CCL2 P13500 1/20 0.34
LMNA P02545 1/20 0.34
TP53 P04637 1/20 0.34
CHRM2 P08172 1/20 0.34
CYP3A4 P08684 1/20 0.34
CHRM1 P11229 1/20 0.34
DRD2 P14416 1/20 0.34
ADRA2B P18089 1/20 0.34
ADRA2C P18825 1/20 0.34
NFKB1 P19838 1/20 0.34
CHRM3 P20309 1/20 0.34
SLC6A2 P23975 1/20 0.34
HTR2C P28335 1/20 0.34
ADRA1A P35348 1/20 0.34
HRH1 P35367 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2136144 1.00 HTR2A (0.38) HTR2AHTR6KDM4ECYP2D6BRD4
SCHEMBL6763868 0.87 HTR2A (0.38) HTR2AHTR6KDM4ECYP2D6BRD4
SCHEMBL15863401 0.82 HTR2A (0.40) HTR2AHTR6KDM4ECYP2D6BRD4
SCHEMBL5183638 0.80 HTR2A (0.39) HTR2AHTR6KDM4ECYP2D6BRD4
SCHEMBL4925283 0.78 HTR2A (0.38) HTR2AHTR6KDM4ECYP2D6BRD4
SCHEMBL812667 0.78 HTR2A (0.38) HTR2AHTR6KDM4ECYP2D6BRD4
SCHEMBL6440197 0.78 HTR2A (0.38) HTR2AHTR6KDM4ECYP2D6BRD4
SCHEMBL5278165 0.78 HTR2A (0.38) HTR2AHTR6KDM4ECYP2D6BRD4
SCHEMBL3798506 0.78 HTR2A (0.38) HTR2AHTR6KDM4ECYP2D6BRD4
SCHEMBL7800583 0.78 MEN1 (0.34) MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114805650-B Metallocene catalyst for preparing cycloolefin copolymer and preparation method thereof 东华工程科技股份有限公司 2022-12-30 CN claimed
CN-114805650-A Metallocene catalyst for preparing cycloolefin copolymer and preparation method thereof 东华工程科技股份有限公司 2022-07-29 CN claimed
CN-110770265-B Catalyst system and method of use thereof 尤尼威蒂恩技术有限责任公司 2023-05-05 CN disclosed
CN-114805650-B Metallocene catalyst for preparing cycloolefin copolymer and preparation method thereof 东华工程科技股份有限公司 2022-12-30 CN disclosed
CN-114805650-B Metallocene catalyst for preparing cycloolefin copolymer and preparation method thereof 东华工程科技股份有限公司 2022-12-30 CN disclosed
CN-114805650-A Metallocene catalyst for preparing cycloolefin copolymer and preparation method thereof 东华工程科技股份有限公司 2022-07-29 CN disclosed
CN-114805650-A Metallocene catalyst for preparing cycloolefin copolymer and preparation method thereof 东华工程科技股份有限公司 2022-07-29 CN disclosed