SCHEMBL812667

SCHEMBL812667

Cl[Zr](Cl)C1C=Cc2ccccc21

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 2/20 0.38
HTR6 P50406 1/20 0.37
SIGMAR1 Q99720 2/20 0.31
KDM4E B2RXH2 2/20 0.31
BRD4 O60885 1/20 0.31
CCL2 P13500 1/20 0.31
LMNA P02545 1/20 0.31
TP53 P04637 1/20 0.31
CHRM2 P08172 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2D6 P10635 1/20 0.31
CHRM1 P11229 1/20 0.31
DRD2 P14416 1/20 0.31
ADRA2B P18089 1/20 0.31
ADRA2C P18825 1/20 0.31
NFKB1 P19838 1/20 0.31
CHRM3 P20309 1/20 0.31
SLC6A2 P23975 1/20 0.31
HTR2C P28335 1/20 0.31
ADRA1A P35348 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5278165 0.87 HTR2A (0.38) HTR2AHTR6SIGMAR1KDM4EBRD4
SCHEMBL15863401 0.82 HTR2A (0.40) HTR2AHTR6SIGMAR1KDM4EBRD4
Hydrochloric Acid SCHEMBL8157131 0.81 CYP2D6 (0.30) CYP2D6
SCHEMBL5183638 0.80 HTR2A (0.39) HTR2AHTR6SIGMAR1KDM4EBRD4
SCHEMBL8679364 0.80
Hydrochloric Acid SCHEMBL8163469 0.80
Chloromethane SCHEMBL3682989 0.79 HTR6 (0.33) HTR2AHTR6SIGMAR1KDM4EBRD4
Chloromethane SCHEMBL3689975 0.79 SIGMAR1 (0.34) HTR2AHTR6SIGMAR1KDM4EBRD4
Chloromethane SCHEMBL7608709 0.79 BRD4 (0.33) HTR2AHTR6SIGMAR1KDM4EBRD4
SCHEMBL2136144 0.78 HTR2A (0.38) HTR2AHTR6SIGMAR1KDM4EBRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 236 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2915824-B1 METALLOCENE LIGANDS, METALLOCENE COMPOUNDS AND METALLOCENE CATALYSTS, THEIR SYNTHESIS AND THEIR USE FOR THE POLYMERIZATION OF OLEFINS LUMMUS NOVOLEN TECHNOLOGY GMBH (DE) 2022-05-25 EP claimed
EP-3344385-A1 ALUMINUM ALKYLS WITH PENDANT OLEFINS ON CLAYS ExxonMobil Chemical Patents Inc. (US) 2018-07-11 EP claimed
WO-2017039994-A1 ALUMINUM ALKYLS WITH PENDANT OLEFINS ON CLAYS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2017-03-09 WO claimed
EP-1737893-A1 PHOSPHORUS BRIDGED METALLOCENE COMPOUNDS FOR OLEFIN POLYMERIZATION ExxonMobil Chemical Patents Inc. (US) 2007-01-03 EP claimed
CN-1738678-A Alkene tandem type tetramer-polymerization method SASOL TECH PTY LTD (ZA) 2006-02-22 CN claimed
WO-2005108435-A1 PHOSPHORUS BRIDGED METALLOCENE COMPOUNDS FOR OLEFIN POLYMERIZATION EXXONMOBIL CHEMICAL PATENTS INC. (US) 2005-11-17 WO claimed
US-6281320-B1 POLYOLEFIN CATALYST UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION 2001-08-28 US claimed
US-6414090-B1 None US disclosed
EP-4692042-A1 COMPOUND, POLYMERIZABLE COMPOSITION, HOLOGRAM RECORDING MEDIUM, POLYMER, OPTICAL MATERIAL, AND OPTICAL COMPONENT Mitsubishi Chemical Corporation (JP) 2026-02-11 EP disclosed
US-20260028312-A1 COMPOUND, POLYMERIZABLE COMPOSITION, HOLOGRAM RECORDING MEDIUM, POLYMER, OPTICAL MATERIAL, AND OPTICAL COMPONENT MITSUBISHI CHEMICAL CORPORATION (JP) 2026-01-29 US disclosed
US-20250206731-A1 COMPOUND, POLYMERIZABLE COMPOSITION, POLYMER, HOLOGRAPHIC RECORDING MEDIUM, OPTICAL MATERIAL, AND OPTICAL COMPONENT MITSUBISHI CHEMICAL CORPORATION (JP) 2025-06-26 US disclosed
US-20250122178-A1 COMPOUND, POLYMERIZABLE COMPOSITION, POLYMER, HOLOGRAPHIC RECORDING MEDIUM, OPTICAL MATERIAL, AND OPTICAL COMPONENT MITSUBISHI CHEMICAL CORPORATION (JP) 2025-04-17 US disclosed
EP-3476871-B1 PREPARATION METHOD FOR AN OLEFIN POLYMER LG CHEMICAL LTD (KR) 2024-05-22 EP disclosed
EP-0406912-A2 Process for polymerizing olefins MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1991-01-09 EP disclosed
EP-0397195-A2 A composition comprising an epoxy compound DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1990-11-14 EP disclosed
EP-0366290-A2 Process for producing olefin polymers CHISSO CORPORATION (JP) 1990-05-02 EP disclosed
EP-0339571-A1 Process for preparation of ethylene polymers SHOWA DENKO KABUSHIKI KAISHA (JP) 1989-11-02 EP disclosed
CN-87107013-A Method for changing melting point and molecular weight of polyolefin by using metallocene catalyst system 1988-10-19 CN disclosed
EP-0284708-A1 Metallocene catalyst systems for olefin polymerization having a silicon hydrocarbyl bridge. FINA TECHNOLOGY, INC. (US) 1988-10-05 EP disclosed
EP-0283164-A2 Cyclo-olefinic random copolymer, olefinic random copolymer, and process for producing cyclo-olefinic random copolymers MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1988-09-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260028312-A1 COMPOUND, POLYMERIZABLE COMPOSITION, HOLOGRAM RECORDING MEDIUM, POLYMER, OPTICAL MATERIAL, AND OPTICAL COMPONENT CHRM1, CHRM2, NOX1 HTR2A 2246/4885HTR6 1861/4885SIGMAR1 136/4885
US-20250206731-A1 COMPOUND, POLYMERIZABLE COMPOSITION, POLYMER, HOLOGRAPHIC RECORDING MEDIUM, OPTICAL MATERIAL, AND OPTICAL COMPONENT H1-0, H1-3, H1-2 HTR2A 2607/4885HTR6 2435/4885SIGMAR1 593/4885
US-20250122178-A1 COMPOUND, POLYMERIZABLE COMPOSITION, POLYMER, HOLOGRAPHIC RECORDING MEDIUM, OPTICAL MATERIAL, AND OPTICAL COMPONENT H1-0, H1-2, CCNB2 HTR2A 1213/4885HTR6 2452/4885SIGMAR1 1167/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.