Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 6/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 5/20 | 0.38 |
| ▸ | DRD1 | P21728 | 2/20 | 0.38 |
| ▸ | DRD4 | P21917 | 2/20 | 0.38 |
| ▸ | DRD5 | P21918 | 2/20 | 0.38 |
| ▸ | USP5 | P45974 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.37 |
| ▸ | BCL9 | O00512 | 2/20 | 0.37 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KDM2B | Q8NHM5 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21361410 | 0.91 | DRD2 (0.44) | DRD2SCN9ADRD3DRD1DRD4 | |
| SCHEMBL21361413 | 0.82 | SCN9A (0.47) | SCN9ANPSR1TSHRGAAMEN1 | |
| SCHEMBL23102112 | 0.80 | MAPT (0.49) | OPRK1ALOX15TSHRKCNH2MEN1 | |
| SCHEMBL23102215 | 0.77 | NPSR1 (0.46) | SCN9AUSP5OPRK1NPSR1TSHR | |
| SCHEMBL23102082 | 0.77 | NPSR1 (0.46) | SCN9AUSP5OPRK1NPSR1TSHR | |
| SCHEMBL24755310 | 0.77 | NPSR1 (0.46) | SCN9AUSP5OPRK1NPSR1TSHR | |
| SCHEMBL21361570 | 0.77 | SCN9A (0.48) | DRD2SCN9ADRD3DRD1DRD4 | |
| SCHEMBL21361421 | 0.77 | SCN9A (0.48) | DRD2SCN9ADRD3DRD1DRD4 | |
| SCHEMBL24755316 | 0.76 | HSD11B1 (0.40) | SCN9AOPRK1NPSR1ALOX15TSHR | |
| SCHEMBL23102066 | 0.76 | NPSR1 (0.46) | SCN9AOPRK1NPSR1TSHRGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019178510-A1 | TRIAZACYCLODODECANSULFONAMIDE (\"TCD\")-BASED PROTEIN SECRETION INHIBITORS | KEZAR LIFE SCIENCES (US) | 2019-09-19 | — | — | WO | disclosed |