SCHEMBL21361792

SCHEMBL21361792

C=C(OCCCCOC)c1ccc(C(C)=O)cc1

nearest known ligand 0.51

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.51
GAA P10253 1/20 0.50
ALDH1A1 P00352 3/20 0.45
TDP1 Q9NUW8 2/20 0.42
POLB P06746 1/20 0.42
APEX1 P27695 1/20 0.42
HTT P42858 1/20 0.42
KMT2A Q03164 2/20 0.40
HPGD P15428 2/20 0.40
MAPT P10636 2/20 0.40
LMNA P02545 1/20 0.40
RAB9A P51151 1/20 0.40
HRH3 Q9Y5N1 2/20 0.39
HDAC6 Q9UBN7 1/20 0.38
MAOB P27338 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19627836 0.95 L3MBTL1 (0.47) L3MBTL1GAAALDH1A1TDP1POLB
SCHEMBL24022673 0.85 MAPT (0.50) ALDH1A1TDP1POLBKMT2AMAPT
SCHEMBL678806 0.83 TDP1 (0.56) L3MBTL1GAAALDH1A1TDP1HPGD
SCHEMBL26889603 0.83 TDP1 (0.49) L3MBTL1GAAALDH1A1TDP1HPGD
SCHEMBL14848389 0.81 TDP1 (0.55) L3MBTL1GAAALDH1A1TDP1HPGD
SCHEMBL26889034 0.81 GAA (0.45) L3MBTL1GAAALDH1A1TDP1POLB
SCHEMBL26889570 0.81 GAA (0.45) L3MBTL1GAAALDH1A1TDP1POLB
SCHEMBL25645464 0.81 L3MBTL1 (0.41) L3MBTL1GAAALDH1A1POLBKMT2A
SCHEMBL12369617 0.79 TSHR (0.53) L3MBTL1GAAALDH1A1TDP1KMT2A
SCHEMBL17340005 0.78 MAPT (0.46) L3MBTL1ALDH1A1TDP1POLBKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019178150-A1 THERMOPLASTIC FOAM ARTICLES NIKE INNOVATE C.V. (US) 2019-09-19 WO disclosed
WO-2019178154-A1 A METHOD FOR MAKING A THERMOPLASTIC FOAM ARTICLE NIKE INNOVATE C.V. (US) 2019-09-19 WO disclosed