Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.45 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.45 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17340005 | 0.92 | MAPT (0.46) | MAPTRAB9ANPC1CASP1ALDH1A1 | |
| SCHEMBL17340007 | 0.86 | ABCB11 (0.52) | MAPTRAB9ANPC1CASP1ALDH1A1 | |
| SCHEMBL21361792 | 0.85 | L3MBTL1 (0.51) | MAPTRAB9AALDH1A1TDP1POLB | |
| SCHEMBL19627836 | 0.81 | L3MBTL1 (0.47) | MAPTRAB9AALDH1A1TDP1POLB | |
| SCHEMBL17340006 | 0.81 | MAPT (0.46) | MAPTRAB9ANPC1CASP1ALDH1A1 | |
| SCHEMBL12736802 | 0.80 | SMN1; SMN2 (0.46) | MAPTRAB9ANPC1ALDH1A1CA1 | |
| SCHEMBL2389583 | 0.80 | TDP1 (0.57) | MAPTRAB9AALDH1A1CA1CA2 | |
| SCHEMBL15693338 | 0.78 | MAPT (0.79) | MAPTRAB9ANPC1ALDH1A1CA1 | |
| SCHEMBL6132617 | 0.77 | MAPT (0.77) | MAPTRAB9ANPC1ALDH1A1CA1 | |
| SCHEMBL7324122 | 0.77 | MAPT (0.77) | MAPTRAB9ANPC1ALDH1A1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3910000-A1 | SUSTAINABLE PBT COMPOSITIONS WITH IMPROVED COLOR CAPABILITY USING THE PURIFIED TEREPHTHALIC ACID PROCESS | SHPP Global Technologies B.V. (NL) | 2021-11-17 | — | — | EP | disclosed |