Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | KDM6A | O15550 | 1/20 | 0.38 |
| ▸ | KDM4A | O75164 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KDM5C | P41229 | 1/20 | 0.38 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.38 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.38 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 2/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.32 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.32 |
| ▸ | GDA | Q9Y2T3 | 2/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21362200 | 0.83 | KDM4E (0.35) | KDM4EKDM6AKDM4ACYP2C9CYP2C19 | |
| SCHEMBL21372044 | 0.82 | PI4KA (0.37) | KDM4EKDM6AKDM4ACYP2C9CYP2C19 | |
| SCHEMBL24504446 | 0.74 | ADORA2A (0.36) | KDM4EPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL19152544 | 0.68 | KDM4E (0.38) | KDM4EKDM6AKDM4ACYP2C9CYP2C19 | |
| SCHEMBL25665451 | 0.68 | ALDH1A1 (0.41) | KDM4EPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL21356495 | 0.65 | BRD4 (0.38) | KDM4EKDM6AKDM4ACYP2C9CYP2C19 | |
| SCHEMBL20224922 | 0.65 | CDK2 (0.40) | ADORA2AADORA1CRBNGDARAB9A | |
| SCHEMBL21372050 | 0.64 | PI4KA (0.38) | ADORA2AADORA1ALDH1A1 | |
| Isocaffiene SCHEMBL515995 | 0.64 | LMNA (0.57) | KDM4EPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL21362194 | 0.63 | ADORA2A (0.32) | ADORA2AADORA1GDAPIK3CDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3765474-B1 | CYCLOPENTANE-BASED MODULATORS OF STING (STIMULATOR OF INTERFERON GENES) | PFIZER (US) | 2022-06-15 | — | — | EP | disclosed |
| WO-2019175776-A1 | CYCLOPENTANE-BASED MODULATORS OF STING (STIMULATOR OF INTERFERON GENES) | PFIZER INC. (US) | 2019-09-19 | — | — | WO | disclosed |