SCHEMBL21362277

SCHEMBL21362277

O=C(NC1CCCCC1)c1cn(Cc2ccncc2F)c2c(F)ccc(F)c12

nearest known ligand 0.79

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CHRM1 P11229 15/20 0.79

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18644828 0.89 CHRM1 (1.00) CHRM1
SCHEMBL20979774 0.89 CHRM1 (1.00) CHRM1
SCHEMBL21362312 0.87 CHRM1 (0.80) CHRM1
SCHEMBL21362316 0.85 CHRM1 (0.78) CHRM1
SCHEMBL18614835 0.81 CHRM1 (1.00) CHRM1
SCHEMBL18614836 0.81 CHRM1 (1.00) CHRM1
SCHEMBL20481703 0.81 CHRM1 (1.00) CHRM1
SCHEMBL21362263 0.80 CHRM1 (0.60) CHRM1
Hydrochloric Acid SCHEMBL20481687 0.80 CHRM1 (0.98) CHRM1
Hydrochloric Acid SCHEMBL18614870 0.80 CHRM1 (0.98) CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3347349-B1 FLUOROINDOLE DERIVATIVES AS MUSCARINIC M1 RECEPTOR POSITIVE ALLOSTERIC MODULATORS SUVEN LIFE SCIENCES LTD (IN) 2019-09-18 EP disclosed