SCHEMBL21362274

Cn1cnc2c(ncn2[C@@H]2C[C@H](OP(=O)(O)S)[C@@H](O)[C@H]2OP(=O)(O)OC[C@@H]2C[C@@H](F)[C@H](n3cnc4c(=O)n(C)cnc43)O2)c1=O

nearest known ligand 0.41

Predicted protein targets (top 3)

	gene	UniProt	supporting neighbours	confidence
▸	RNASEL	Q05823	3/20	0.41

▸	STING1	Q86WV6	8/20	0.40

▸	TYMP	P19971	1/20	0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL24504643	1.00	RNASEL (0.41)	RNASELSTING1TYMP
SCHEMBL21362212	0.89	RNASEL (0.54)	RNASELSTING1
SCHEMBL21362251	0.85	STING1 (0.47)	RNASELSTING1
SCHEMBL21362248	0.83	STING1 (0.47)	RNASELSTING1
SCHEMBL21362245	0.82	STING1 (0.44)	RNASELSTING1
SCHEMBL21362332	0.80	STING1 (0.39)	STING1TYMP
SCHEMBL24504465	0.75	RNASEL (0.41)	RNASEL
SCHEMBL22990411	0.74	STING1 (0.48)	RNASELSTING1
SCHEMBL24504673	0.71	NT5E (0.49)	STING1
SCHEMBL23692627	0.70	TYMP (0.41)	STING1TYMP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2019175776-A1	CYCLOPENTANE-BASED MODULATORS OF STING (STIMULATOR OF INTERFERON GENES)	PFIZER INC. (US)	2019-09-19	—	—	WO	disclosed