Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 14/20 | 0.39 |
| ▸ | TYMP | P19971 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21362245 | 0.84 | STING1 (0.44) | STING1 | |
| SCHEMBL21362251 | 0.81 | STING1 (0.47) | STING1 | |
| SCHEMBL24504643 | 0.80 | RNASEL (0.41) | STING1TYMP | |
| SCHEMBL21362274 | 0.80 | RNASEL (0.41) | STING1TYMP | |
| SCHEMBL21362212 | 0.75 | RNASEL (0.54) | STING1 | |
| SCHEMBL23692644 | 0.70 | TAS1R3 (0.41) | STING1TYMP | |
| SCHEMBL22990411 | 0.69 | STING1 (0.48) | STING1 | |
| SCHEMBL23692627 | 0.69 | TYMP (0.41) | STING1TYMP | |
| SCHEMBL31685307 | 0.69 | P2RY1 (0.51) | — | |
| SCHEMBL21133326 | 0.68 | P2RX3 (0.55) | STING1TYMP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3765474-B1 | CYCLOPENTANE-BASED MODULATORS OF STING (STIMULATOR OF INTERFERON GENES) | PFIZER (US) | 2022-06-15 | — | — | EP | disclosed |
| WO-2019175776-A1 | CYCLOPENTANE-BASED MODULATORS OF STING (STIMULATOR OF INTERFERON GENES) | PFIZER INC. (US) | 2019-09-19 | — | — | WO | disclosed |