Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 4/20 | 0.44 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | AKR1B10 | O60218 | 4/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 4/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
| ▸ | TTR | P02766 | 4/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GMNN | O75496 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2609806 | 1.00 | PTGS2 (0.44) | PTGS2THRBAKR1B10AKR1B1MAOB | |
| SCHEMBL13777695 | 0.96 | PTGS2 (0.40) | PTGS2THRBAKR1B10AKR1B1MAOB | |
| SCHEMBL13777751 | 0.95 | THRB (0.44) | PTGS2THRBAKR1B10AKR1B1MAOB | |
| SCHEMBL2609802 | 0.94 | THRB (0.43) | PTGS2THRBAKR1B10AKR1B1MAOB | |
| SCHEMBL21362473 | 0.94 | THRB (0.43) | PTGS2THRBAKR1B10AKR1B1MAOB | |
| SCHEMBL13777681 | 0.94 | THRB (0.45) | PTGS2THRBAKR1B10AKR1B1MAOB | |
| SCHEMBL13777731 | 0.90 | THRB (0.45) | PTGS2THRBAKR1B10AKR1B1MAOB | |
| SCHEMBL13777758 | 0.90 | THRB (0.45) | PTGS2THRBAKR1B10AKR1B1MAOB | |
| SCHEMBL20464162 | 0.90 | PTGS2 (0.46) | PTGS2AKR1B10AKR1B1CYP2D6MEN1 | |
| SCHEMBL20464157 | 0.89 | PTGS2 (0.42) | PTGS2THRBAKR1B10AKR1B1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190285997-A1 | IMAGE FORMING APPARATUS | RICOH COMPANY, LTD. (JP) | 2019-09-19 | — | — | US | disclosed |