SCHEMBL21362536

SCHEMBL21362536

C=CCOP(=O)(OC1CCCCC1)C1CCCCC1

nearest known ligand 0.36

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.36
NPC1 O15118 1/20 0.31
MAPT P10636 1/20 0.31
RAB9A P51151 1/20 0.31
ALDH1A1 P00352 1/20 0.30
GAA P10253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9114844 0.88 NPC1 (0.35) NPC1MAPTRAB9AALDH1A1GAA
SCHEMBL11882757 0.78 ACHE (0.37) ACHENPC1MAPTRAB9AALDH1A1
SCHEMBL575288 0.78 ACHE (0.48) ACHEGAA
SCHEMBL575155 0.77 ACHE (0.43) ACHEGAA
SCHEMBL11519442 0.77 ACHE (0.39) ACHE
SCHEMBL9114848 0.77 ACHE (0.36) ACHENPC1MAPTRAB9AALDH1A1
SCHEMBL575665 0.75 ACHE (0.45) ACHEGAA
SCHEMBL30686723 0.75 ACHE (0.33) ACHE
SCHEMBL29723017 0.73 ACHE (0.36) ACHE
SCHEMBL575480 0.71 ACHE (0.47) ACHEGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10421872-B1 Stain resistant coating composition THE SHERWIN-WILLIAMS COMPANY (US) 2019-09-24 US claimed
US-10421872-B1 Stain resistant coating composition THE SHERWIN-WILLIAMS COMPANY (US) 2019-09-24 US disclosed