Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 5/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | KDM1A | O60341 | 2/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20157992 | 0.78 | TOP2A (0.40) | MAPTL3MBTL1HPGDNPC1RAB9A | |
| SCHEMBL20157895 | 0.68 | TOP2A (0.37) | MAPTL3MBTL1HPGDNPC1RAB9A | |
| SCHEMBL20158171 | 0.67 | LMNA (0.41) | SLC6A2MAPTL3MBTL1HPGDNPC1 | |
| SCHEMBL11883 | 0.67 | ACHE (0.62) | MAPTL3MBTL1HPGDNPC1RAB9A | |
| SCHEMBL9774382 | 0.66 | LMNA (0.44) | NPC1RAB9ASMN1; SMN2KMT2AKDM1A | |
| SCHEMBL84653 | 0.65 | LMNA (0.47) | HPGDNPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL16798294 | 0.65 | LMNA (0.47) | NPC1RAB9ASMN1; SMN2KMT2AKDM1A | |
| SCHEMBL21362664 | 0.65 | ABL1 (0.37) | MAPTL3MBTL1HPGDNPC1RAB9A | |
| SCHEMBL20158035 | 0.64 | ABL1 (0.36) | MAPTL3MBTL1HPGDNPC1RAB9A | |
| SCHEMBL29447058 | 0.63 | ACHE (0.62) | MAPTL3MBTL1HPGDNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3539960-A1 | NITROGENOUS MACROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION AND APPLICATION THEREOF | Luoxin Pharmaceutical (Shanghai) Co., Ltd. (CN) | 2019-09-18 | — | — | EP | disclosed |