Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.48 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | TRPV3 | Q8NET8 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.41 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.41 |
| ▸ | ITGAV | P06756 | 1/20 | 0.41 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27308031 | 0.95 | HPGD (0.45) | HPGDEPHX1CD274RAB9ANPC1 | |
| SCHEMBL26125032 | 0.92 | SIGMAR1 (0.42) | HPGDEPHX1CD274TRPV3ALDH1A1 | |
| SCHEMBL16726956 | 0.84 | USP2 (0.38) | HPGDCD274TRPV3ALDH1A1KMT2A | |
| SCHEMBL8644471 | 0.84 | GBA1 (0.44) | — | |
| SCHEMBL5172580 | 0.80 | HPGD (0.50) | HPGDEPHX1RAB9ANPC1EPHX2 | |
| SCHEMBL18886611 | 0.80 | EPHX1 (0.49) | HPGDEPHX1RAB9ANPC1EPHX2 | |
| SCHEMBL23004863 | 0.79 | NPC1 (0.47) | HPGDEPHX1RAB9ANPC1EPHX2 | |
| SCHEMBL8091688 | 0.79 | EPHX1 (0.40) | HPGDEPHX1RAB9ANPC1EPHX2 | |
| SCHEMBL24324182 | 0.78 | SIGMAR1 (0.40) | HPGDEPHX2ALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL23004957 | 0.78 | NPC1 (0.49) | HPGDEPHX1RAB9ANPC1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109219601-B | Method for preparing optically active beraprost | 奇诺因药物和化学工厂私人有限公司 | 2022-08-09 | — | — | CN | disclosed |
| EP-3440065-B1 | PROCESS FOR THE PREPARATION OF OPTICALLY ACTIVE BERAPROST | EUROAPI HUNGARY LLC (HU) | 2022-06-08 | — | — | EP | disclosed |
| US-10421737-B2 | Process for the preparation of optically active Beraprost | CHINOIN PHARMACEUTICAL AND CHEMICAL WORKS PRIVATE COMPANY LTD. (HU) | 2019-09-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10421737-B2 | Process for the preparation of optically active Beraprost | CYP51A1, DDOST, SQLE | HPGD 937/4885EPHX1 152/4885CD274 3719/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.