Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.47 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | PLAU | P00749 | 2/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | PGK1 | P00558 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2135021 | 0.87 | CA1 (0.47) | SMN1; SMN2KDM4EALDH1A1KMT2AHPGD | |
| SCHEMBL2137567 | 0.86 | KMT2A (0.47) | SMN1; SMN2KDM4EALDH1A1KMT2AHPGD | |
| SCHEMBL10206279 | 0.84 | KDM4E (0.43) | SMN1; SMN2KDM4EALDH1A1KMT2ATSHR | |
| SCHEMBL2133084 | 0.82 | MEN1 (0.47) | ALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL2137037 | 0.82 | ADORA2B (0.43) | KDM4EGAAMAPT | |
| SCHEMBL24363124 | 0.81 | ALDH1A1 (0.53) | SMN1; SMN2CDK5CDK5R1KDM4EALDH1A1 | |
| SCHEMBL2134013 | 0.79 | KCNQ3 (0.49) | SMN1; SMN2KDM4EALDH1A1GAAMAPT | |
| SCHEMBL2136669 | 0.79 | ADORA2A (0.43) | — | |
| SCHEMBL1466169 | 0.78 | ALDH1A1 (0.55) | SMN1; SMN2KDM4EALDH1A1KMT2ATSHR | |
| SCHEMBL2136869 | 0.78 | KDM4E (0.46) | SMN1; SMN2KDM4EALDH1A1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2445884-B1 | 4-AMINOPICOLINATES AND THEIR USE AS HERBICIDES | SYNGENTA LTD (GB) | 2013-02-13 | — | — | EP | disclosed |
| US-20120100990-A1 | 4 -AMINOPICOLINATES AND THEIR USE AS HERBICIDES | SYNGENTA CROP PROTECTION LLC (US) | 2012-04-26 | — | — | US | disclosed |
| US-20120100990-A1 | 4 -AMINOPICOLINATES AND THEIR USE AS HERBICIDES | SYNGENTA CROP PROTECTION LLC (US) | 2012-04-26 | — | — | US | disclosed |
| US-20120100990-A1 | 4 -AMINOPICOLINATES AND THEIR USE AS HERBICIDES | SYNGENTA CROP PROTECTION LLC (US) | 2012-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120100990-A1 | 4 -AMINOPICOLINATES AND THEIR USE AS HERBICIDES | DDT, DAO, NPM1 | SMN1; SMN2 3068/4885CDK5 1012/4885CDK5R1 2212/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.