SCHEMBL213629

SCHEMBL213629

COC(=O)C(C)(C)C=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9449123 0.80 DGAT1 (0.44)
SCHEMBL9449125 0.80 DGAT1 (0.44)
SCHEMBL28872527 0.80 PRSS1 (0.31)
SCHEMBL1515115 0.78
SCHEMBL65239 0.76
SCHEMBL320537 0.76 DGAT1 (0.46)
SCHEMBL12638857 0.76
SCHEMBL14949704 0.74 DGAT1 (0.39)
SCHEMBL8283733 0.74 DGAT1 (0.39)
SCHEMBL9342926 0.74 DGAT1 (0.39)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 348 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-8217708-A None JP disclosed
US-20260138998-A1 GLP-1 RECEPTOR AGONISTS AND METHODS OF USE MERCK SHARP & DOHME LLC (US) 2026-05-21 US disclosed
EP-3364967-B1 FERROPORTIN INHIBITORS VIFOR INT AG (CH) 2026-05-20 EP disclosed
EP-4739390-A1 2-(1H-INDOL-4-YL)METHYL)2H-INDAZOLE DERIVATIVES AS FACTOR B INHIBITORS Sitala Bio Ltd (GB) 2026-05-13 EP disclosed
US-20260055062-A1 HETEROCYCLIC INHIBITORS OF MCT4 Vettore, LLC 2026-02-26 US disclosed
US-12492171-B2 Heterocyclic inhibitors of MCT4 Vettore, LLC (US) 2025-12-09 US disclosed
EP-3365339-B1 NOVEL FERROPORTIN INHIBITORS VIFOR INT AG (CH) 2025-07-16 EP disclosed
WO-2025129104-A1 COMPOUNDS, COMPOSITIONS, AND METHODS OF USING THEREOF SIONNA THERAPEUTICS INC. (US) 2025-06-19 WO disclosed
US-20250179072-A1 TRICYCLIC AKR1C3 DEPENDENT KARS INHIBITORS NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH, INC. 2025-06-05 US disclosed
WO-2025008451-A1 2-(1H-INDOL-4-YL)METHYL)2H-INDAZOLE DERIVATIVES AS FACTOR B INHIBITORS SITALA BIO LTD (GB) 2025-01-09 WO disclosed
US-5371297-A Preparation of aldehydes BASF AKTIENGESELLSCHAFT (DE) 1994-12-06 US disclosed
US-5364970-A Rhodium catalyst, selectivity, preparation of methyl alpha-formylisobutyrate SHELL OIL COMPANY (US) 1994-11-15 US disclosed
EP-0621075-A2 Novel rhodium-containing catalyst KURARAY CO., LTD. (JP) 1994-10-26 EP disclosed
EP-0589302-A1 Process for the preparation of aldehydes BASF Aktiengesellschaft (DE) 1994-03-30 EP disclosed
US-5084487-A Polyetherpolyimine copolymers for reaction injection molding BASF AKTIENGESELLSCHAFT (DE) 1992-01-28 US disclosed
US-4853454-A POLYETHER- OR -ESTERURETHANES AND POLYIMINECURING AGENTS; MOLDINGKMATERIALS; SOLVENT-FREE; SPRAYABLE PROTECTIVE COATINGS BASF AKTIENGESELLSCHAFT (DE) 1989-08-01 US disclosed
US-4789691-A REACTING POLYISOCYANATE, POLYAZOMETHINE, AND AROMATIC POLYAMINES BASF AKTIENGESELLSCHAFT (DE) 1988-12-06 US disclosed
EP-0023636-B1 PYRAZOLIN-5-ON-YL-METHYL-(DI)THIOPHOSPHORIC ACID ESTERS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS PESTICIDES BASF Aktiengesellschaft (DE) 1982-11-17 EP disclosed
US-4346087-A CORROSION RESISTANCE TOHO CHEMICAL INDUSTRY CO., LTD. (JP) 1982-08-24 US disclosed
EP-0023636-A1 Pyrazolin-5-on-yl-methyl-(di)thiophosphoric acid esters, process for their preparation and their use as pesticides BASF Aktiengesellschaft (DE) 1981-02-11 EP disclosed