Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.56 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.41 |
| ▸ | THRA | P10827 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9671267 | 0.84 | SIGMAR1 (0.75) | SIGMAR1KCNH2HRH3TAAR1THRA | |
| SCHEMBL9670507 | 0.82 | SIGMAR1 (0.79) | SIGMAR1KCNH2HRH3TAAR1THRA | |
| SCHEMBL9670726 | 0.82 | SIGMAR1 (0.79) | SIGMAR1KCNH2HRH3TAAR1THRA | |
| SCHEMBL170113 | 0.79 | HSD17B10 (0.58) | THRATHRB | |
| SCHEMBL9670561 | 0.77 | SIGMAR1 (0.64) | SIGMAR1KCNH2HRH3TAAR1 | |
| SCHEMBL947879 | 0.77 | HSD17B10 (0.61) | THRATHRB | |
| SCHEMBL177025 | 0.77 | HSD17B10 (0.61) | THRATHRB | |
| SCHEMBL2773891 | 0.77 | HSD17B10 (0.61) | THRATHRB | |
| SCHEMBL4745509 | 0.77 | HSD17B10 (0.61) | THRATHRB | |
| SCHEMBL7794684 | 0.77 | HSD17B10 (0.61) | THRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2981590-B1 | LANTHANIDE COMPLEXES COMPRISING AT LEAST TWO BETAINE GROUPS, WHICH CAN BE USED AS LUMINESCENT MARKERS | ECOLE NORMALE SUPERIEURE LYON (FR) | 2019-09-18 | — | — | EP | disclosed |