Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.64 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.63 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.61 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.52 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | DRD1 | P21728 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9671700 | 0.93 | HRH3 (0.74) | SIGMAR1KCNH2HRH3TAAR1LMNA | |
| SCHEMBL9671267 | 0.92 | SIGMAR1 (0.75) | SIGMAR1KCNH2HRH3TAAR1 | |
| SCHEMBL14902842 | 0.91 | ALDH1A1 (0.56) | SIGMAR1KCNH2HRH3TAAR1LMNA | |
| SCHEMBL19146986 | 0.91 | SIGMAR1 (0.55) | SIGMAR1KCNH2HRH3TAAR1LMNA | |
| SCHEMBL9670726 | 0.90 | SIGMAR1 (0.79) | SIGMAR1KCNH2HRH3TAAR1 | |
| SCHEMBL9670507 | 0.90 | SIGMAR1 (0.79) | SIGMAR1KCNH2HRH3TAAR1 | |
| SCHEMBL554550 | 0.89 | AOC3 (0.59) | SIGMAR1KCNH2HRH3TAAR1AOC3 | |
| SCHEMBL2475962 | 0.89 | ESR1 (0.55) | SIGMAR1KCNH2HRH3TAAR1LMNA | |
| SCHEMBL10677993 | 0.89 | TAAR1 (0.76) | SIGMAR1KCNH2HRH3TAAR1AOC3 | |
| SCHEMBL1376233 | 0.89 | SIGMAR1 (0.53) | SIGMAR1KCNH2HRH3TAAR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170114247-A1 | PROCESSES FOR MOISTURE SCAVENGING IN PREPARING POLYURETHANE COATINGS AND COMPOSITIONS THEREFOR | Achiewell, LLC | 2017-04-27 | — | — | US | disclosed |
| US-5093370-A | Useful prior to insertion of tracheotomy tube or discission | TOBISHI YAKUHIN KOGYO KABUSHIKI KAISHA (JP) | 1992-03-03 | — | — | US | disclosed |