Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AB1 | P08238 | 4/20 | 0.56 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.56 |
| ▸ | MAP1LC3B | Q9GZQ8 | 2/20 | 0.56 |
| ▸ | MAP1LC3A | Q9H492 | 2/20 | 0.56 |
| ▸ | POLQ | O75417 | 1/20 | 0.56 |
| ▸ | ALB | P02768 | 1/20 | 0.56 |
| ▸ | KDR | P35968 | 1/20 | 0.56 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22023815 | 0.89 | HSP90AB1 (0.68) | HSP90AB1HSP90AA1MAP1LC3BMAP1LC3APOLQ | |
| SCHEMBL22023535 | 0.89 | HSP90AB1 (0.68) | HSP90AB1HSP90AA1MAP1LC3BMAP1LC3APOLQ | |
| SCHEMBL21363030 | 0.89 | HSP90AB1 (0.68) | HSP90AB1HSP90AA1MAP1LC3BMAP1LC3APOLQ | |
| SCHEMBL25906467 | 0.81 | HSP90AB1 (0.57) | HSP90AB1HSP90AA1MAP1LC3BMAP1LC3APOLQ | |
| SCHEMBL25906463 | 0.81 | HSP90AB1 (0.57) | HSP90AB1HSP90AA1MAP1LC3BMAP1LC3APOLQ | |
| SCHEMBL24589015 | 0.81 | HSP90AB1 (0.68) | HSP90AB1HSP90AA1MAP1LC3BMAP1LC3APOLQ | |
| SCHEMBL13644903 | 0.80 | HSP90AB1 (0.73) | HSP90AB1HSP90AA1MAP1LC3BMAP1LC3APOLQ | |
| SCHEMBL17049899 | 0.80 | HSP90AB1 (0.73) | HSP90AB1HSP90AA1MAP1LC3BMAP1LC3APOLQ | |
| SCHEMBL10306489 | 0.80 | HSP90AB1 (0.73) | HSP90AB1HSP90AA1MAP1LC3BMAP1LC3APOLQ | |
| SCHEMBL21363200 | 0.80 | HSP90AB1 (0.73) | HSP90AB1HSP90AA1MAP1LC3BMAP1LC3APOLQ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019178119-A1 | AMINOCOUMARIN COMPOUNDS AND METHODS OF THEIR USE | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2019-09-19 | — | — | WO | disclosed |