SCHEMBL21363360

SCHEMBL21363360

C/C=C\c1c(O)c(Br)c2ccccc2c1C

nearest known ligand 0.33

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.33
ERN1 O75460 1/20 0.32
PADI4 Q9UM07 1/20 0.32
LMNA P02545 1/20 0.32
HTT P42858 1/20 0.32
POLB P06746 1/20 0.32
KDM4E B2RXH2 1/20 0.31
DAO P14920 1/20 0.31
DDO Q99489 1/20 0.31
ESR1 P03372 1/20 0.31
ESR2 Q92731 1/20 0.31
CYP2C19 P33261 1/20 0.31
PTGS1 P23219 2/20 0.30
PTGS2 P35354 2/20 0.30
PKM P14618 1/20 0.30
TTR P02766 1/20 0.30
ALOX5 P09917 1/20 0.30
MAOB P27338 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21765441 0.78 PADI4 (0.44) ERN1PADI4LMNAHTTPOLB
SCHEMBL19261611 0.75 CYP1A2 (0.35) PADI4ESR2
SCHEMBL20858549 0.71 CYP1A2 (0.38) PADI4ESR1ESR2
SCHEMBL29768240 0.70 CYP1A2 (0.33)
SCHEMBL2468887 0.70 POLB (0.48) PADI4LMNAHTTPOLBKDM4E
SCHEMBL19996919 0.68 CXCR5 (0.30)
SCHEMBL4645950 0.68 TSHR (0.44) MAOALMNAPOLBKDM4E
SCHEMBL20405095 0.67 L3MBTL1 (0.40) LMNAHTTKDM4E
SCHEMBL22940624 0.66 CYP1A2 (0.35) PADI4LMNAKDM4E
SCHEMBL19645398 0.66 CXCR5 (0.34) KDM4EESR1ESR2CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3539959-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2019-09-18 EP disclosed