SCHEMBL19645398

SCHEMBL19645398

C/C=C\c1c(/C(=C\C)c2ccccc2C)c(C)c2ccccc2c1C

nearest known ligand 0.34

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CXCR5 P32302 1/20 0.34
FGFR1 P11362 1/20 0.33
FLT1 P17948 1/20 0.33
KDR P35968 1/20 0.33
CHRM3 P20309 1/20 0.32
CYP3A4 P08684 1/20 0.31
CYP2C19 P33261 1/20 0.31
GPR52 Q9Y2T5 1/20 0.31
HPGD P15428 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
MEN1 O00255 1/20 0.30
ESR1 P03372 1/20 0.30
KMT2A Q03164 1/20 0.30
ESR2 Q92731 1/20 0.30
CTNNB1 P35222 1/20 0.30
WNT3A P56704 1/20 0.30
KDM4E B2RXH2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6546142 0.74 CHRM3 (0.39) CHRM3CYP3A4HPGDKMT2AKDM4E
SCHEMBL8733487 0.73 TSHR (0.45) CHRM3GPR52HPGDSMN1; SMN2
SCHEMBL19261611 0.72 CYP1A2 (0.35) CXCR5CYP3A4HPGDESR2
SCHEMBL6546578 0.69 TRPA1 (0.41) CHRM3CYP3A4HPGDSMN1; SMN2MEN1
SCHEMBL20858549 0.67 CYP1A2 (0.38) CYP3A4HPGDESR1ESR2
SCHEMBL29768240 0.66 CYP1A2 (0.33) CYP3A4HPGD
SCHEMBL7925207 0.66 NPC1 (0.42) CHRM3CYP2C19HPGDSMN1; SMN2KMT2A
SCHEMBL6548199 0.66 NPC1 (0.42) CHRM3CYP2C19HPGDSMN1; SMN2KMT2A
SCHEMBL21363360 0.66 MAOA (0.33) CYP2C19ESR1ESR2KDM4E
SCHEMBL19645399 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9831442-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2017-11-28 US disclosed