Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | HBB | P68871 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 5/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.34 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL601646 | 0.91 | KDM4E (0.50) | KDM4EATML3MBTL1ALDH1A1PDK2 | |
| SCHEMBL30293940 | 0.91 | KDM4E (0.50) | KDM4EATML3MBTL1ALDH1A1PDK2 | |
| SCHEMBL24725888 | 0.88 | ALDH1A1 (0.40) | KDM4EATML3MBTL1ALDH1A1MAPT | |
| SCHEMBL21008867 | 0.88 | KDM4E (0.44) | KDM4EATML3MBTL1PDK2POLB | |
| SCHEMBL30077228 | 0.86 | KDM4E (0.46) | KDM4EATML3MBTL1MAPTMEN1 | |
| SCHEMBL12292088 | 0.86 | KDM4E (0.46) | KDM4EATML3MBTL1MAPTMEN1 | |
| SCHEMBL29664894 | 0.86 | KDM4E (0.46) | KDM4EATML3MBTL1MAPTMEN1 | |
| SCHEMBL12171156 | 0.86 | KDM4E (0.46) | KDM4EATML3MBTL1MAPTMEN1 | |
| SCHEMBL390193 | 0.86 | KDM4E (0.46) | KDM4EATML3MBTL1MAPTMEN1 | |
| SCHEMBL17854687 | 0.85 | KDM4E (0.42) | KDM4EATML3MBTL1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190284334-A1 | POLY (SPIROBIFLUORENE) AND ORGANIC ELECTROLUMINESCENT DEVICE | CHANGCHUN INSTITUTE OF APPLIED CHEMISTRY CHINESE ACADEMY OF SCIENCES (CN) | 2019-09-19 | — | — | US | disclosed |