Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GPR3 | P46089 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21364171 | 0.87 | PDK2 (0.44) | PDK2KDM4EHSD17B10ALDH1A1GPR3 | |
| SCHEMBL21364253 | 0.80 | PDK2 (0.44) | PDK2KDM4EALDH1A1GPR3LMNA | |
| SCHEMBL20222373 | 0.80 | PDK2 (0.40) | PDK2KDM4EHSD17B10ALDH1A1GPR3 | |
| SCHEMBL7619444 | 0.80 | PDK2 (0.58) | PDK2KDM4EESR1ESR2ELANE | |
| SCHEMBL18880905 | 0.80 | PDK2 (0.58) | PDK2KDM4EESR1ESR2ELANE | |
| SCHEMBL19013527 | 0.80 | PDK2 (0.58) | PDK2KDM4EESR1ESR2ELANE | |
| SCHEMBL30004202 | 0.80 | PDK2 (0.58) | PDK2KDM4EESR1ESR2ELANE | |
| SCHEMBL4734675 | 0.78 | KDM4E (0.37) | PDK2KDM4EHSD17B10ALDH1A1GPR3 | |
| SCHEMBL29548566 | 0.76 | PDK2 (0.62) | PDK2KDM4EALDH1A1ESR1ESR2 | |
| SCHEMBL6292385 | 0.76 | PDK2 (0.62) | PDK2KDM4EALDH1A1ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190284334-A1 | POLY (SPIROBIFLUORENE) AND ORGANIC ELECTROLUMINESCENT DEVICE | CHANGCHUN INSTITUTE OF APPLIED CHEMISTRY CHINESE ACADEMY OF SCIENCES (CN) | 2019-09-19 | — | — | US | disclosed |