Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 20/20 | 0.63 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.59 |
| ▸ | IGF1R | P08069 | 2/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL21358519 | 0.95 | EGFR (0.58) | EGFRALKIGF1RKCNH2 | |
| SCHEMBL18359226 | 0.87 | EGFR (0.70) | EGFRALKIGF1RKCNH2 | |
| SCHEMBL21363944 | 0.84 | EGFR (0.78) | EGFRALKIGF1RKCNH2 | |
| Trifluoroacetic Acid SCHEMBL21358354 | 0.81 | EGFR (0.72) | EGFRALKIGF1RKCNH2 | |
| SCHEMBL19027763 | 0.81 | EGFR (0.72) | EGFRALKIGF1RKCNH2 | |
| SCHEMBL19860792 | 0.79 | EGFR (0.70) | EGFRIGF1RKCNH2 | |
| SCHEMBL17670293 | 0.79 | EGFR (0.57) | EGFRALKIGF1RKCNH2 | |
| SCHEMBL31030282 | 0.79 | EGFR (0.57) | EGFRALKIGF1RKCNH2 | |
| SCHEMBL17196870 | 0.78 | EGFR (0.68) | EGFRALKIGF1RKCNH2 | |
| SCHEMBL17792850 | 0.78 | EGFR (0.68) | EGFRALKIGF1RKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019177375-A1 | 2, 4, 5-SUBSTITUTED PYRIMIDINE DERIVATIVES, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING CANCER COMPRISING SAME AS ACTIVE INGREDIENT | 포로노이바이오 주식회사 | 2019-09-19 | — | — | WO | disclosed |