SCHEMBL21364403

SCHEMBL21364403

c1cc(-c2nc3ccccc3nc2-c2cccc3ccccc23)cc(-n2c3ccccc3c3cc4nc5ccccc5n4cc32)c1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAD51 Q06609 2/20 0.36
FLT3 P36888 3/20 0.35
BMX P51813 2/20 0.35
PDE10A Q9Y233 1/20 0.34
ALK Q9UM73 3/20 0.34
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
POLB P06746 1/20 0.33
HSD17B10 Q99714 1/20 0.33
L3MBTL1 Q9Y468 2/20 0.32
KDM4E B2RXH2 1/20 0.31
ATM Q13315 1/20 0.31
TUBB4A P04350 1/20 0.31
TUBB P07437 1/20 0.31
TUBA3C P0DPH7 1/20 0.31
TUBA1B P68363 1/20 0.31
TUBA4A P68366 1/20 0.31
TUBB4B P68371 1/20 0.31
TUBB3 Q13509 1/20 0.31
TUBB2A Q13885 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23917407 0.84 PDE10A (0.42) RAD51PDE10AALKMEN1KMT2A
SCHEMBL23917328 0.80 ALDH1A1 (0.36) FLT3BMXALKMEN1KMT2A
SCHEMBL18877045 0.78 CYP1A2 (0.38) FLT3BMXPDE10AMEN1KMT2A
SCHEMBL12268644 0.78 KDM4E (0.39) FLT3BMXPDE10AMEN1KMT2A
SCHEMBL23917347 0.76 HSD17B10 (0.40) RAD51PDE10AALKMEN1KMT2A
SCHEMBL21622697 0.75 ALDH1A1 (0.38) ALKPOLBL3MBTL1KDM4EATM
SCHEMBL19655308 0.75 L3MBTL1 (0.49) PDE10AMEN1KMT2APOLBHSD17B10
SCHEMBL21717096 0.74 FLT3 (0.36) FLT3BMXL3MBTL1KDM4EATM
SCHEMBL21716794 0.74 FLT3 (0.36) FLT3BMXL3MBTL1KDM4EATM
SCHEMBL19655311 0.74 L3MBTL1 (0.44) RAD51PDE10AMEN1KMT2APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019177243-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING SAME, AND ELECTRONIC DEVICE THEREFOR 덕산네오룩스 주식회사 2019-09-19 WO disclosed