Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.34 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | PLK4 | O00444 | 1/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10210065 | 0.92 | MAPT (0.39) | MEN1KMT2AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL29004068 | 0.81 | MAPT (0.51) | MEN1KMT2AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL714013 | 0.77 | ALDH1A1 (0.41) | MEN1KMT2AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL14806811 | 0.77 | MAPK14 (0.39) | ALDH1A1SMN1; SMN2LMNANPC1RAB9A | |
| SCHEMBL21915668 | 0.77 | CYP3A4 (0.43) | MEN1KMT2AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL862821 | 0.77 | COMT (0.40) | MEN1KMT2AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL17197413 | 0.77 | ESR1 (0.39) | MEN1KMT2AMAPTSMN1; SMN2MAPK1 | |
| SCHEMBL721818 | 0.76 | TDO2 (0.39) | ALDH1A1MAPTMAPK1CYP2A6NPC1 | |
| SCHEMBL20806202 | 0.76 | COMT (0.39) | MEN1KMT2AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL23055925 | 0.75 | MAPK1 (0.44) | MEN1KMT2AALDH1A1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190284334-A1 | POLY (SPIROBIFLUORENE) AND ORGANIC ELECTROLUMINESCENT DEVICE | CHANGCHUN INSTITUTE OF APPLIED CHEMISTRY CHINESE ACADEMY OF SCIENCES (CN) | 2019-09-19 | — | — | US | disclosed |