Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.51 |
| ▸ | RAB9A | P51151 | 6/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | GFER | P55789 | 1/20 | 0.51 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | NTMT1 | Q9BV86 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | CCR4 | P51679 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | CCR1 | P32246 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL298722 | 0.86 | KDM4E (0.54) | PDE10AKDM4ERAB9AALDH1A1MAPT | |
| SCHEMBL6840490 | 0.77 | PDE10A (1.00) | PDE10AKDM4ERAB9AALDH1A1MAPT | |
| SCHEMBL30606303 | 0.77 | PDE10A (1.00) | PDE10AKDM4ERAB9AALDH1A1MAPT | |
| SCHEMBL1741719 | 0.77 | CYP19A1 (0.79) | PDE10AKDM4ERAB9AALDH1A1MAPT | |
| SCHEMBL13663963 | 0.75 | ASIC3 (0.41) | PDE10AKDM4ERAB9AALDH1A1MAPT | |
| SCHEMBL18157876 | 0.75 | CCR4 (0.46) | RAB9AALDH1A1MAPTHSD17B10MAPK1 | |
| SCHEMBL10025209 | 0.75 | SREBF2 (0.54) | KDM4ERAB9AALDH1A1MAPTPKM | |
| SCHEMBL4436213 | 0.74 | SREBF2 (0.67) | PDE10AKDM4ERAB9AALDH1A1MAPT | |
| SCHEMBL252304 | 0.74 | PDE10A (0.64) | PDE10AKDM4ERAB9AALDH1A1MAPT | |
| SCHEMBL13020808 | 0.74 | PDE10A (0.64) | PDE10AKDM4ERAB9AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11547698-B2 | Aryl hydrocarbon receptor modulators | ARIAGEN, INC. (US) | 2023-01-10 | — | — | US | disclosed |
| US-20190330201-A1 | ARYL HYDROCARBON RECEPTOR MODULATORS | AHR PHARMACEUTICALS, INC. | 2019-10-31 | — | — | US | disclosed |
| US-20190307731-A1 | ARYL HYDROCARBON RECEPTOR MODULATOR | ARIAGEN, INC. (US) | 2019-10-10 | — | — | US | disclosed |
| US-20190284149-A1 | ARYL HYDROCARBON RECEPTOR MODULATOR | ARIAGEN, INC. (US) | 2019-09-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190307731-A1 | ARYL HYDROCARBON RECEPTOR MODULATOR | AHR, ARNT, NR1H4 | PDE10A 4170/4885KDM4E 2566/4885RAB9A 924/4885 |
| US-11547698-B2 | Aryl hydrocarbon receptor modulators | AHR, ARNT, CNR1 | PDE10A 3478/4885KDM4E 2197/4885RAB9A 1954/4885 |
| US-20190284149-A1 | ARYL HYDROCARBON RECEPTOR MODULATOR | AHR, ARNT, NR1H4 | PDE10A 4087/4885KDM4E 2472/4885RAB9A 901/4885 |
| US-20190330201-A1 | ARYL HYDROCARBON RECEPTOR MODULATORS | AHR, ARNT, CNR1 | PDE10A 3478/4885KDM4E 2197/4885RAB9A 1954/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.