SCHEMBL2136622

SCHEMBL2136622

C[Si]1(C)CCC(CC(COCC2CO2)OCC2CO2)O[Si]1(C)C

nearest known ligand 0.37

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.37
SMN1; SMN2 Q16637 1/20 0.36
TDP1 Q9NUW8 1/20 0.35
TSHR P16473 2/20 0.33
MAPK1 P28482 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28285401 0.78 ALDH1A1 (0.46) ALDH1A1SMN1; SMN2TDP1TSHRMAPK1
Water SCHEMBL15797971 0.76 ALDH1A1 (0.45) ALDH1A1SMN1; SMN2TDP1TSHRMAPK1
SCHEMBL10369309 0.73 TSHR (0.50) ALDH1A1SMN1; SMN2TDP1TSHRMAPK1
SCHEMBL28432642 0.73 SMN1; SMN2 (0.45) ALDH1A1SMN1; SMN2TDP1TSHRMAPK1
SCHEMBL22592522 0.73 ALDH1A1 (0.50) ALDH1A1SMN1; SMN2TDP1TSHRMAPK1
SCHEMBL17011976 0.73 ALDH1A1 (0.50) ALDH1A1SMN1; SMN2TDP1TSHRMAPK1
SCHEMBL36444 0.73 ALDH1A1 (0.50) ALDH1A1SMN1; SMN2TDP1TSHRMAPK1
SCHEMBL10080567 0.71 ALDH1A1 (0.49) ALDH1A1SMN1; SMN2TDP1TSHRMAPK1
SCHEMBL28044163 0.71 SMN1; SMN2 (0.31) ALDH1A1SMN1; SMN2TSHR
SCHEMBL9388311 0.70 ALDH1A1 (0.33) ALDH1A1SMN1; SMN2TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2809724-B1 PROCESS FOR THE PRODUCTION OF PET FOAMS AND PET FOAMS OBTAINED WITH SAID PROCESS DIAB INT AB (SE) 2016-01-13 EP disclosed
US-7863391-B2 Organopolysiloxane and curable silicone composition that contains aforementioned organopolysiloxane DOW CORNING TORAY COMPANY, LTD. (JP) 2011-01-04 US disclosed
US-20080207848-A1 Organopolysiloxane and Curable Silicone Composition that Contains Aforementioned Organopolysiloxane DOW CORNING TORAY CO., LTD. (JP) 2008-08-28 US disclosed
EP-1819753-B1 ORGANOPOLYSILOXANE AND CURABLE SILICONE COMPOSITION THAT CONTAINS AFOREMENTIONED ORGANOPOLYSILOXANE DOW CORNING TORAY CO LTD (JP) 2008-04-02 EP disclosed
EP-1819753-A1 ORGANOPOLYSILOXANE AND CURABLE SILICONE COMPOSITION THAT CONTAINS AFOREMENTIONED ORGANOPOLYSILOXANE Dow Corning Toray Co., Ltd. (JP) 2007-08-22 EP disclosed
WO-2006038638-A1 ORGANOPOLYSILOXANE AND CURABLE SILICONE COMPOSITION THAT CONTAINS AFOREMENTIONED ORGANOPOLYSILOXANE DOW CORNING TORAY CO., LTD. (JP) 2006-04-13 WO disclosed