Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | RAF1 | P04049 | 13/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 6/20 | 0.38 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.38 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.38 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20711411 | 0.81 | HPGD (0.44) | ALDH1A1HPGDTSHRNPSR1KDM4E | |
| SCHEMBL8964947 | 0.79 | HCAR2 (0.39) | MAPK1ALDH1A1HPGDTSHRNPSR1 | |
| SCHEMBL14684024 | 0.79 | ALDH1A1 (0.41) | MAPK1ALDH1A1TSHRNPSR1 | |
| SCHEMBL2678390 | 0.77 | ALDH1A1 (0.37) | MAPK1ALDH1A1L3MBTL1HPGDTSHR | |
| SCHEMBL15751264 | 0.76 | CLK1 (0.35) | MAPK1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL5010782 | 0.76 | ALDH1A1 (0.36) | MAPK1ALDH1A1L3MBTL1HPGDTSHR | |
| SCHEMBL24958731 | 0.75 | MAPK1 (0.44) | MAPK1ALDH1A1L3MBTL1TSHRATM | |
| SCHEMBL130301 | 0.75 | MAPK1 (0.44) | MAPK1ALDH1A1L3MBTL1ATMKDM4E | |
| SCHEMBL13260686 | 0.73 | MAPK1 (0.43) | MAPK1ALDH1A1L3MBTL1HPGDTSHR | |
| SCHEMBL24369745 | 0.73 | ALDH1A1 (0.46) | MAPK1ALDH1A1L3MBTL1HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190284149-A1 | ARYL HYDROCARBON RECEPTOR MODULATOR | ARIAGEN, INC. (US) | 2019-09-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190284149-A1 | ARYL HYDROCARBON RECEPTOR MODULATOR | AHR, ARNT, NR1H4 | MAPK1 2003/4885ALDH1A1 488/4885L3MBTL1 3264/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.