⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10273176 | 0.54 | — | — | |
| SCHEMBL6964773 | 0.53 | — | — | |
| SCHEMBL18901147 | 0.53 | — | — | |
| SCHEMBL19580748 | 0.53 | — | — | |
| SCHEMBL17484184 | 0.53 | — | — | |
| SCHEMBL30537823 | 0.45 | — | — | |
| SCHEMBL9937577 | 0.43 | NOTUM (0.38) | — | |
| SCHEMBL8207543 | 0.41 | — | — | |
| SCHEMBL22278145 | 0.41 | HTR2A (0.33) | — | |
| SCHEMBL433960 | 0.38 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240092819-A1 | NOVEL LIGANDS FOR ASIALOGLYCOPROTEIN RECEPTOR | SANOFI SA (FR) | 2024-03-21 | — | — | US | disclosed |
| US-11891386-B2 | Indole compounds and their use | ARIAGEN, INC. (CA) | 2024-02-06 | — | — | US | disclosed |
| US-20230145074-A1 | Indole Compounds and Their Use | ARIAGEN, INC. (US) | 2023-05-11 | — | — | US | disclosed |
| US-20230054194-A1 | Methods of Treating Cancer | ARIAGEN, INC. (US) | 2023-02-23 | — | — | US | disclosed |
| US-20220389002-A1 | Chiral Indole Compounds and Their Use | ARIAGEN, INC. (US) | 2022-12-08 | — | — | US | disclosed |
| US-11459322-B2 | Indole compounds and their use | ARIAGEN, INC. (US) | 2022-10-04 | — | — | US | disclosed |
| US-11390621-B2 | Chiral indole compounds and their use | ARIAGEN, INC. (US) | 2022-07-19 | — | — | US | disclosed |
| EP-3956327-A1 | CHIRAL INDOLE COMPOUNDS AND THEIR USE | Ariagen, Inc. (US) | 2022-02-23 | — | — | EP | disclosed |
| CN-113906021-A | Chiral indole compound and application thereof | 阿里根公司 | 2022-01-07 | — | — | CN | disclosed |
| EP-3883605-A1 | METHODS OF TREATING CANCER | Ariagen, Inc. (US) | 2021-09-29 | — | — | EP | disclosed |
| WO-2020214740-A9 | CHIRAL INDOLE COMPOUNDS AND THEIR USE | ARIAGEN, INC. (US) | 2020-11-26 | — | — | WO | disclosed |
| US-20200354353-A1 | Indole Compounds and Their Use | ARIAGEN, INC. (US) | 2020-11-12 | — | — | US | disclosed |
| WO-2020214740-A1 | CHIRAL INDOLE COMPOUNDS AND THEIR USE | ARIAGEN, INC. (US) | 2020-10-22 | — | — | WO | disclosed |
| EP-3713937-A2 | INDOLE COMPOUNDS AS ARYL HYDROCARBON RECEPTOR (AHR) MODULATORS | Ariagen, Inc. (US) | 2020-09-30 | — | — | EP | disclosed |
| CN-111587249-A | Indole compounds and uses thereof | 阿里根公司 | 2020-08-25 | — | — | CN | disclosed |
| US-20120101100-A1 | HETEROCYCLIC UREA DERIVATIVES AND METHODS OF USE THEREOF-211 | ASTRAZENECA AB (SE) | 2012-04-26 | — | — | US | disclosed |
| EP-2262801-A1 | HETEROCYCLIC UREA DERIVATIVES AND METHODS OF USE THEREOF-211 | AstraZeneca AB (SE) | 2010-12-22 | — | — | EP | disclosed |
| WO-2009106885-A1 | HETEROCYCLIC UREA DERIVATIVES AND METHODS OF USE THEREOF-211 | ASTRAZENECA AB (SE) | 2009-09-03 | — | — | WO | disclosed |
| EP-0127847-A1 | 7-Oxo-4-thia-1-azabicyclo(3.2.0)hept-2-ene derivatives | HOECHST UK LIMITED (GB) | 1984-12-12 | — | — | EP | disclosed |
| US-4307116-A | BACTERICIDES | RHONE-POULENC INDUSTRIES (FR) | 1981-12-22 | — | — | US | disclosed |