Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL78520 | 0.76 | DGAT1 (0.46) | DGAT1 | |
| SCHEMBL21008320 | 0.76 | DGAT1 (0.37) | DGAT1 | |
| SCHEMBL3970722 | 0.74 | DGAT1 (0.36) | DGAT1 | |
| SCHEMBL29399642 | 0.74 | — | — | |
| SCHEMBL9784171 | 0.72 | DGAT1 (0.34) | DGAT1 | |
| SCHEMBL12682757 | 0.72 | DGAT1 (0.34) | DGAT1 | |
| Thiourea SCHEMBL5840778 | 0.72 | DGAT1 (0.34) | DGAT1 | |
| SCHEMBL11621321 | 0.71 | DGAT1 (0.42) | DGAT1 | |
| Hydrazine SCHEMBL10794464 | 0.71 | DGAT1 (0.42) | DGAT1 | |
| SCHEMBL16045685 | 0.71 | DGAT1 (0.42) | DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019178129-A1 | SUBSTITUTED IMIDAZOPYRIDINES AS INHIBITORS OF PLASMA KALLIKREIN AND USES THEREOF | SHIRE HUMAN GENETIC THERAPIES, INC. (US) | 2019-09-19 | — | — | WO | disclosed |