SCHEMBL3970722

SCHEMBL3970722

CC(C)(C)OC(=O)C(=N)N

nearest known ligand 0.36

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
DGAT1 O75907 1/20 0.36
MAOA P21397 1/20 0.32
MAOB P27338 1/20 0.32
NOS1 P29475 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4325034 0.78 DGAT1 (0.39) DGAT1MAOAMAOB
Hydrazine SCHEMBL10794464 0.77 DGAT1 (0.42) DGAT1MAOAMAOB
SCHEMBL6951911 0.77 DGAT1 (0.35) DGAT1MAOAMAOB
SCHEMBL78520 0.76 DGAT1 (0.46) DGAT1
SCHEMBL31524998 0.76 DGAT1 (0.37) DGAT1MAOAMAOB
SCHEMBL27655031 0.76 DGAT1 (0.37) DGAT1MAOAMAOB
SCHEMBL21008320 0.76 DGAT1 (0.37) DGAT1
SCHEMBL21368053 0.74 DGAT1 (0.36) DGAT1
SCHEMBL15279401 0.74 DGAT1 (0.36) DGAT1MAOAMAOB
Guanidine SCHEMBL27275385 0.74 GAA (0.41) DGAT1MAOAMAOBNOS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115745910-A Chemical compound 安塔比奥公司 2023-03-07 CN disclosed
CN-110446708-B Chemical compound 安塔比奥公司 2022-12-02 CN disclosed
CN-114615981-A KRAS G12D inhibitors 米拉蒂治疗股份有限公司 2022-06-10 CN disclosed
CN-106279369-B Antifungal agent and application thereof 奇达拉治疗公司 2020-02-11 CN disclosed
CN-110003079-A For making the ligand of imaging cardiac innervation 兰休斯医疗成像公司 2019-07-12 CN disclosed
CN-105622463-B For making the ligand of imaging cardiac innervation 兰休斯医疗成像公司 2019-02-22 CN disclosed
CN-104334555-A Isoxazole beta-lactamase inhibitors CUBIST PHARM INC 2015-02-04 CN disclosed
EP-2680873-A2 ANTIFUNGAL AGENTS AND USES THEREOF Seachaid Pharmaceuticals, Inc. (US) 2014-01-08 EP disclosed
WO-2013029182-A1 STABLE PEPTIDE-BASED FURIN INHIBITORS SOCPRA SCIENCES SANTÉ ET HUMAINES S.E.C. (CA) 2013-03-07 WO disclosed
WO-2013029180-A1 STABLE PEPTIDE-BASED PACE4 INHIBITORS SOCPRA SCIENCES SANTÉ ET HUMAINES S.E.C. (CA) 2013-03-07 WO disclosed
WO-2003093267-A1 7-ARYL-3,9-DIAZABICYCLO(3.3.1)NON-6-ENE DERIVATIVES AND THEIR USE AS RENIN INHIBITORS IN THE TREATMENT OF HYPERTENSION, CARDIOVASCULAR OR RENAL DISEASES ACTELION PHARMACEUTICALS LTD (CH) 2003-11-13 WO disclosed
CN-1379666-A Non-peptide GnRH agents, methods and intermediates for their preparation AGOURON PHARMA (US) 2002-11-13 CN disclosed
CN-1305492-A Pyrazinone protease inhibitors DIMENSIONAL PHARM INC (US) 2001-07-25 CN disclosed
CN-1305454-A Anthranilic acid derivatives as inhibitors of CGMP phosphodiesterase FUJISAWA PHARMACEUTICAL CO (JP) 2001-07-25 CN disclosed
CN-1303365-A Benzamide and sulfonamide substituted aminoguanidines and alkoxyguanidines as protease inhibitors DIMENSIONAL PHARM INC (US) 2001-07-11 CN disclosed
EP-1089966-A1 NOVEL COMPOUNDS USEFUL IN PAIN MANAGEMENT AstraZeneca AB (SE) 2001-04-11 EP disclosed
EP-1089965-A1 NOVEL COMPOUNDS AstraZeneca AB (SE) 2001-04-11 EP disclosed
EP-0730590-B1 ISOXAZOLINE AND ISOXAZOLE FIBRINOGEN RECEPTOR ANTAGONISTS DU PONT PHARM CO (US) 2001-01-17 EP disclosed
WO-1999067204-A1 NOVEL COMPOUNDS ASTRAZENECA AB (SE) 1999-12-29 WO disclosed
WO-1999067205-A1 NOVEL COMPOUNDS USEFUL IN PAIN MANAGEMENT ASTRAZENECA AB (SE) 1999-12-29 WO disclosed