Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLS | O94925 | 20/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21368591 | 0.83 | GLS (0.59) | GLS | |
| SCHEMBL21368592 | 0.79 | GLS (0.53) | GLS | |
| SCHEMBL14987105 | 0.77 | GLS (0.76) | GLS | |
| SCHEMBL14987276 | 0.73 | GLS (0.78) | GLS | |
| SCHEMBL19920004 | 0.72 | GLS (0.62) | GLS | |
| SCHEMBL14986949 | 0.71 | GLS (1.00) | GLS | |
| SCHEMBL21369016 | 0.71 | GLS (0.54) | GLS | |
| SCHEMBL15782779 | 0.69 | GLS (0.78) | GLS | |
| SCHEMBL19920149 | 0.68 | GLS (0.56) | GLS | |
| SCHEMBL21368571 | 0.68 | GLS (0.77) | GLS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2782570-B1 | HETEROCYCLIC INHIBITORS OF GLUTAMINASE | CALITHERA BIOSCIENCES INC (US) | 2019-09-18 | — | — | EP | disclosed |