Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | OGA | O60502 | 14/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21370127 | 0.98 | SMN1; SMN2 (0.62) | SMN1; SMN2LMNAOGAALDH1A1HTT | |
| SCHEMBL22079257 | 0.86 | SMN1; SMN2 (0.51) | SMN1; SMN2LMNAOGAALDH1A1HTT | |
| SCHEMBL22079383 | 0.86 | SMN1; SMN2 (0.49) | SMN1; SMN2LMNAOGAALDH1A1HTT | |
| SCHEMBL22079715 | 0.84 | SMN1; SMN2 (0.48) | SMN1; SMN2LMNAOGAALDH1A1HTT | |
| SCHEMBL21370130 | 0.83 | ALDH1A1 (0.67) | SMN1; SMN2LMNAOGAALDH1A1HTT | |
| SCHEMBL16113448 | 0.81 | SMN1; SMN2 (0.76) | SMN1; SMN2OGA | |
| SCHEMBL22078765 | 0.81 | SMN1; SMN2 (0.68) | SMN1; SMN2OGA | |
| SCHEMBL20281964 | 0.79 | SMN1; SMN2 (0.74) | SMN1; SMN2OGA | |
| SCHEMBL16113454 | 0.79 | SMN1; SMN2 (1.00) | SMN1; SMN2OGAHTT | |
| SCHEMBL22697065 | 0.79 | OGA (0.49) | OGA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4327814-A2 | MORPHOLINYL, PIPERAZINYL, OXAZEPANYL AND DIAZEPANYL O-GLYCOPROTEIN-2-ACETAMIDO-2-DEOXY-3-D-GLUCOPYRANOSIDASE INHIBITORS | Biogen MA Inc. (US) | 2024-02-28 | — | — | EP | disclosed |
| EP-3891146-B1 | MORPHOLINYL, PIPERAZINYL, OXAZEPANYL AND DIAZEPANYL DERIVATIVES USEFUL AS O-GLYCOPROTEIN-2-ACETAMIDO-2-DEOXY-3-D-GLUCOPYRANOSIDASE INHIBITORS | BIOGEN MA INC (US) | 2023-09-27 | — | — | EP | disclosed |
| EP-4186899-A1 | O-GLYCOPROTEIN-2-ACETAMIDO-2-DEOXY-3-D-GLYCOPYRANOSIDASE INHIBITORS | Biogen MA Inc. (US) | 2023-05-31 | — | — | EP | disclosed |
| EP-3765458-B1 | O-GLYCOPROTEIN-2-ACETAMIDO-2-DEOXY-3-D-GLYCOPYRANOSIDASE INHIBITORS | BIOGEN MA INC (US) | 2023-01-11 | — | — | EP | disclosed |
| WO-2020117961-A1 | MORPHOLINYL, PIPERAZINYL, OXAZEPANYL AND DIAZEPANYL O-GLYCOPROTEIN-2-ACETAMIDO-2-DEOXY-3-D-GLUCOPYRANOSIDASE INHIBITORS | BIOGEN MA INC. (US) | 2020-06-11 | — | — | WO | disclosed |
| WO-2019178191-A1 | O-GLYCOPROTEIN-2-ACETAMIDO-2-DEOXY-3-D-GLYCOPYRANOSIDASE INHIBITORS | BIOGEN MA INC. (US) | 2019-09-19 | — | — | WO | disclosed |