Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.67 |
| ▸ | OGA | O60502 | 15/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25625991 | 0.92 | ALDH1A1 (0.56) | ALDH1A1OGASMN1; SMN2HTTLMNA | |
| SCHEMBL21370127 | 0.84 | SMN1; SMN2 (0.62) | ALDH1A1OGASMN1; SMN2HTTLMNA | |
| SCHEMBL21369461 | 0.83 | SMN1; SMN2 (0.64) | ALDH1A1OGASMN1; SMN2HTTLMNA | |
| SCHEMBL16114197 | 0.82 | OGA (0.67) | OGA | |
| SCHEMBL22079257 | 0.82 | SMN1; SMN2 (0.51) | ALDH1A1OGASMN1; SMN2HTTLMNA | |
| SCHEMBL22079383 | 0.82 | SMN1; SMN2 (0.49) | ALDH1A1OGASMN1; SMN2HTTLMNA | |
| SCHEMBL16113387 | 0.81 | OGA (0.71) | ALDH1A1OGASMN1; SMN2HTTLMNA | |
| SCHEMBL22079715 | 0.81 | SMN1; SMN2 (0.48) | ALDH1A1OGASMN1; SMN2HTTLMNA | |
| SCHEMBL22433477 | 0.78 | LMNA (0.46) | ALDH1A1OGASMN1; SMN2HTTLMNA | |
| SCHEMBL21370037 | 0.77 | OGA (0.44) | ALDH1A1OGASMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019178191-A1 | O-GLYCOPROTEIN-2-ACETAMIDO-2-DEOXY-3-D-GLYCOPYRANOSIDASE INHIBITORS | BIOGEN MA INC. (US) | 2019-09-19 | — | — | WO | disclosed |