SCHEMBL21369907

SCHEMBL21369907

c1ccc(-c2cc(-c3cc(-c4cc5ccccc5c5ccccc45)cc(-n4c5ccccc5c5ccc(-c6ccccc6)cc54)c3)nc(-c3ccc4oc5ccccc5c4c3)c2)cc1

nearest known ligand 0.32

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
SIRT2 Q8IXJ6 1/20 0.32
SIRT1 Q96EB6 1/20 0.32
PLA2G2A P14555 2/20 0.32
PLA2G4A P47712 2/20 0.32
MAPK1 P28482 1/20 0.32
KMT2A Q03164 1/20 0.32
KDM4E B2RXH2 1/20 0.31
ALDH1A1 P00352 1/20 0.31
MAPT P10636 1/20 0.31
HPGD P15428 1/20 0.31
ALOX15 P16050 1/20 0.31
TSHR P16473 1/20 0.31
CASP1 P29466 1/20 0.31
CASP7 P55210 1/20 0.31
HSD17B10 Q99714 1/20 0.31
PLA2G10 O15496 1/20 0.31
CYP2A6 P11509 1/20 0.30
CYP11B1 P15538 1/20 0.30
PRKDC P78527 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21369768 0.96 SIRT2 (0.34) SIRT2SIRT1PLA2G2APLA2G4AMAPK1
SCHEMBL21369798 0.94 SIRT2 (0.32) SIRT2SIRT1PLA2G2APLA2G4AMAPK1
SCHEMBL21370308 0.93 PLA2G2A (0.35) PLA2G2APLA2G4AKMT2AKDM4EALDH1A1
SCHEMBL21369891 0.92 MAPK1 (0.33) SIRT2SIRT1PLA2G2APLA2G4AMAPK1
SCHEMBL21370294 0.91 PLA2G2A (0.36) PLA2G2APLA2G4AKMT2AKDM4EALDH1A1
SCHEMBL21370379 0.90 CYP11B1 (0.35) MAPK1KDM4EALDH1A1MAPTHPGD
SCHEMBL21370215 0.89 CYP11B1 (0.36) MAPK1KMT2AKDM4EALDH1A1MAPT
SCHEMBL21369894 0.89 SIRT2 (0.33) SIRT2SIRT1PLA2G2APLA2G4AMAPK1
SCHEMBL21370240 0.89 SIRT2 (0.34) SIRT2SIRT1PLA2G2APLA2G4AMAPK1
SCHEMBL21370263 0.88 CYP11B1 (0.36) MAPK1KMT2AKDM4EALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190288215-A1 COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME SOULBRAIN CO., LTD. (KR) 2019-09-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190288215-A1 COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME CRY1, CYP1A1, CYP1B1 SIRT2 2833/4885SIRT1 2186/4885PLA2G2A 4334/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.