Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OGA | O60502 | 16/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24862806 | 0.87 | OGA (0.56) | OGAOPRK1 | |
| SCHEMBL21359507 | 0.87 | OGA (0.56) | OGAOPRK1 | |
| SCHEMBL21359465 | 0.87 | OGA (0.56) | OGAOPRK1 | |
| SCHEMBL21359496 | 0.87 | OGA (0.56) | OGAOPRK1 | |
| SCHEMBL21359522 | 0.87 | OGA (0.56) | OGAOPRK1 | |
| SCHEMBL21370279 | 0.86 | OGA (0.44) | OGAALDH1A1ACKR3OPRK1SMN1; SMN2 | |
| SCHEMBL21369566 | 0.86 | OGA (0.44) | OGAALDH1A1ACKR3OPRK1SMN1; SMN2 | |
| SCHEMBL21369448 | 0.82 | OGA (0.52) | OGAALDH1A1ACKR3OPRK1SMN1; SMN2 | |
| SCHEMBL21370134 | 0.79 | OGA (0.36) | OGAALDH1A1OPRK1SMN1; SMN2 | |
| SCHEMBL22079713 | 0.79 | OGA (0.38) | OGAACKR3OPRK1SMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019178191-A1 | O-GLYCOPROTEIN-2-ACETAMIDO-2-DEOXY-3-D-GLYCOPYRANOSIDASE INHIBITORS | BIOGEN MA INC. (US) | 2019-09-19 | — | — | WO | disclosed |