Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OGA | O60502 | 17/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21359541 | 0.87 | OGA (0.51) | OGAOPRK1 | |
| SCHEMBL21359493 | 0.81 | OGA (0.51) | OGA | |
| SCHEMBL21370128 | 0.79 | OGA (0.40) | OGAOPRK1SMN1; SMN2ALDH1A1 | |
| SCHEMBL21369448 | 0.78 | OGA (0.52) | OGALMNAOPRK1SMN1; SMN2ALDH1A1 | |
| SCHEMBL21369594 | 0.78 | OGA (0.37) | OGALMNAOPRK1 | |
| SCHEMBL21370042 | 0.78 | OGA (0.37) | OGALMNAOPRK1 | |
| SCHEMBL21370037 | 0.77 | OGA (0.44) | OGALMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL21370122 | 0.77 | OGA (0.38) | OGALMNAOPRK1 | |
| SCHEMBL21370279 | 0.75 | OGA (0.44) | OGAOPRK1SMN1; SMN2ALDH1A1 | |
| SCHEMBL21370045 | 0.74 | ALDH1A1 (0.47) | OGALMNASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4186899-A1 | O-GLYCOPROTEIN-2-ACETAMIDO-2-DEOXY-3-D-GLYCOPYRANOSIDASE INHIBITORS | Biogen MA Inc. (US) | 2023-05-31 | — | — | EP | disclosed |
| WO-2019178191-A1 | O-GLYCOPROTEIN-2-ACETAMIDO-2-DEOXY-3-D-GLYCOPYRANOSIDASE INHIBITORS | BIOGEN MA INC. (US) | 2019-09-19 | — | — | WO | disclosed |