Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 3/20 | 0.38 |
| ▸ | TNNC1 | P63316 | 5/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.33 |
| ▸ | SGPL1 | O95470 | 1/20 | 0.33 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.33 |
| ▸ | GPR183 | P32249 | 1/20 | 0.33 |
| ▸ | CERS2 | Q96G23 | 1/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.33 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.31 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16714816 | 0.86 | FDPS (0.38) | FDPSALDH1A1TSHRSMPD1 | |
| SCHEMBL16594935 | 0.79 | FDPS (0.40) | FDPSALDH1A1TSHRSMPD1 | |
| SCHEMBL11233675 | 0.77 | TSHR (0.42) | FDPSALDH1A1TSHRSMPD1 | |
| SCHEMBL18577887 | 0.77 | TSHR (0.42) | FDPSALDH1A1TSHRSMPD1 | |
| SCHEMBL8993606 | 0.73 | TSHR (0.35) | FDPSALDH1A1TSHR | |
| SCHEMBL517213 | 0.71 | FDPS (0.33) | FDPSTSHR | |
| SCHEMBL27961116 | 0.70 | FDPS (0.37) | FDPSALDH1A1TSHRSMPD1 | |
| SCHEMBL10386164 | 0.70 | — | — | |
| SCHEMBL27961118 | 0.70 | FDPS (0.37) | FDPSALDH1A1TSHRSMPD1 | |
| SCHEMBL141848 | 0.69 | MEN1 (0.47) | FDPSTNNC1S1PR1SGPL1S1PR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220274985-A1 | PROCESSES FOR PREPARING TOLL-LIKE RECEPTOR MODULATOR COMPOUNDS | GILEAD SCIENCES, INC. | 2022-09-01 | — | — | US | disclosed |
| US-20190282576-A1 | TOLL LIKE RECEPTOR MODULATOR COMPOUNDS | GILEAD SCIENCES, INC. | 2019-09-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220274985-A1 | PROCESSES FOR PREPARING TOLL-LIKE RECEPTOR MODULATOR COMPOUNDS | TLR4, TLR3, TLR6 | FDPS 1257/4885TNNC1 3756/4885S1PR1 220/4885 |
| US-20190282576-A1 | TOLL LIKE RECEPTOR MODULATOR COMPOUNDS | TLR8, TLR3, TLR6 | FDPS 1519/4885TNNC1 4422/4885S1PR1 370/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.