Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ERN1 | O75460 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2075254 | 0.83 | LMNA (0.62) | NPSR1ALDH1A1GAAL3MBTL1PTGDR2 | |
| SCHEMBL12438312 | 0.82 | MAOB (0.45) | NPSR1ALDH1A1GAAPTGDR2LMNA | |
| SCHEMBL276480 | 0.79 | EPAS1 (0.49) | GAAPTGDR2LMNAKMT2AAR | |
| SCHEMBL276011 | 0.78 | PTGDR2 (0.46) | NPSR1ALDH1A1L3MBTL1PTGDR2LMNA | |
| SCHEMBL276112 | 0.78 | PTGDR2 (0.46) | NPSR1ALDH1A1GAAL3MBTL1PTGDR2 | |
| SCHEMBL275629 | 0.77 | LMNA (0.61) | NPSR1ALDH1A1GAAL3MBTL1PTGDR2 | |
| SCHEMBL1128457 | 0.77 | AR (0.62) | ALDH1A1GAAL3MBTL1ARMAPK1 | |
| SCHEMBL1643529 | 0.77 | PTGDR2 (0.43) | NPSR1ALDH1A1GAAPTGDR2LMNA | |
| SCHEMBL5606306 | 0.77 | ACHE (0.49) | NPSR1ALDH1A1L3MBTL1PTGDR2LMNA | |
| SCHEMBL21129706 | 0.76 | LMNA (0.62) | NPSR1ALDH1A1GAALMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019178480-A1 | PYRAZOLE-CONTAINING MACROPHAGE MIGRATION INHIBITORY FACTOR INHIBITORS | YALE UNIVERSITY (US) | 2019-09-19 | — | — | WO | disclosed |