Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 4/20 | 0.33 |
| ▸ | FEN1 | P39748 | 4/20 | 0.33 |
| ▸ | FABP6 | P51161 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13424834 | 0.80 | ALDH1A1 (0.40) | GRM5ALDH1A1GAAMAPTHSD17B10 | |
| SCHEMBL31167912 | 0.76 | ALOX5AP (0.38) | GRM5ALDH1A1GAAMAPTHSD17B10 | |
| SCHEMBL3327459 | 0.76 | GRM5 (0.36) | GRM5ALDH1A1GAAMAPTHSD17B10 | |
| SCHEMBL3324553 | 0.76 | GRM5 (0.36) | GRM5ALDH1A1GAAMAPTHSD17B10 | |
| SCHEMBL14150282 | 0.72 | STIM1 (0.34) | — | |
| SCHEMBL23860863 | 0.70 | ALDH1A1 (0.40) | GRM5ALDH1A1GAAMAPTHSD17B10 | |
| SCHEMBL29364018 | 0.70 | ALDH1A1 (0.40) | GRM5ALDH1A1GAAMAPTHSD17B10 | |
| SCHEMBL6107503 | 0.70 | ALDH1A1 (0.40) | GRM5ALDH1A1GAAMAPTHSD17B10 | |
| SCHEMBL12654074 | 0.69 | GRM5 (0.40) | GRM5ALDH1A1GAAMAPTHSD17B10 | |
| SCHEMBL18307148 | 0.69 | GRM5 (0.54) | GRM5ALDH1A1GAAMAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3182973-B1 | TRICYCLIC NITROGEN CONTAINING COMPOUNDS FOR TREATING NEISSERIA GONORRHOEA INFECTION | GLAXOSMITHKLINE IP DEV LTD (GB) | 2019-09-18 | — | — | EP | disclosed |