SCHEMBL213731

SCHEMBL213731

CC(=O)ON=C(C)c1nccs1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RBBP9 O75884 5/20 0.67
CYP1A2 P05177 3/20 0.63
CYP2D6 P10635 3/20 0.63
CYP2C19 P33261 3/20 0.63
CASP3 P42574 2/20 0.63
SENP8 Q96LD8 2/20 0.63
SENP7 Q9BQF6 2/20 0.63
SENP6 Q9GZR1 2/20 0.63
MAPT P10636 1/20 0.63
ALDH1A1 P00352 4/20 0.62
KMT2A Q03164 2/20 0.62
L3MBTL1 Q9Y468 1/20 0.62
HKDC1 Q2TB90 1/20 0.38
MAOA P21397 1/20 0.36
MAOB P27338 1/20 0.36
RAB9A P51151 1/20 0.35
HSD17B10 Q99714 1/20 0.35
PLA2G7 Q13093 1/20 0.35
HSPA9 P38646 1/20 0.35
PLA2G4A P47712 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL212884 0.80 RBBP9 (0.55) RBBP9CYP1A2CYP2D6CYP2C19CASP3
SCHEMBL213922 0.77 RBBP9 (0.52) RBBP9CYP1A2CYP2D6CYP2C19CASP3
SCHEMBL212121 0.76 RBBP9 (0.51) RBBP9CYP1A2CYP2D6CYP2C19CASP3
SCHEMBL1254922 0.75 ALDH1A1 (0.59) RBBP9CYP1A2CYP2D6CYP2C19CASP3
SCHEMBL2948824 0.74
SCHEMBL13237108 0.74
SCHEMBL2948821 0.74
SCHEMBL247631 0.73
SCHEMBL213200 0.72 RBBP9 (0.48) RBBP9CYP1A2CYP2D6CYP2C19CASP3
SCHEMBL17183611 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120077941-A1 POLYMERS FUNCTIONALIZED WITH PROTECTED OXIME COMPOUNDS BRIDGESTONE CORPORATION (JP) 2012-03-29 US claimed
US-8088868-B2 oximation of cojugated homopolymers formed by addtion polymerization of conjugated diene monomer in the presence lanthanide copmpounds as polymerization catalysts; polymers used in the manufacture of tires having reduced hysteresis BRIDGESTONE CORPORATION (JP) 2012-01-03 US claimed
US-20080146745-A1 POLYMERS FUNCTIONALIZED WITH PROTECTED OXIME COMPOUNDS BRIDGESTONE CORPORATION (JP) 2008-06-19 US claimed
US-8541509-B2 Polymers functionalized with protected oxime compounds BRIDGESTONE CORPORATION (JP) 2013-09-24 US disclosed
US-20120077941-A1 POLYMERS FUNCTIONALIZED WITH PROTECTED OXIME COMPOUNDS BRIDGESTONE CORPORATION (JP) 2012-03-29 US disclosed
US-8088868-B2 oximation of cojugated homopolymers formed by addtion polymerization of conjugated diene monomer in the presence lanthanide copmpounds as polymerization catalysts; polymers used in the manufacture of tires having reduced hysteresis BRIDGESTONE CORPORATION (JP) 2012-01-03 US disclosed
US-20080146745-A1 POLYMERS FUNCTIONALIZED WITH PROTECTED OXIME COMPOUNDS BRIDGESTONE CORPORATION (JP) 2008-06-19 US disclosed