SCHEMBL212884

SCHEMBL212884

CON=C(C)c1nccs1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RBBP9 O75884 5/20 0.55
ALDH1A1 P00352 5/20 0.55
KMT2A Q03164 3/20 0.55
L3MBTL1 Q9Y468 1/20 0.55
CYP1A2 P05177 3/20 0.52
CYP2D6 P10635 3/20 0.52
CYP2C19 P33261 3/20 0.52
CASP3 P42574 2/20 0.52
SENP8 Q96LD8 2/20 0.52
SENP7 Q9BQF6 2/20 0.52
SENP6 Q9GZR1 2/20 0.52
MAPT P10636 2/20 0.52
HKDC1 Q2TB90 1/20 0.40
MAOA P21397 1/20 0.38
MAOB P27338 1/20 0.38
MITF O75030 1/20 0.36
HSP90AA1 P07900 1/20 0.36
SMPD3 Q9NY59 1/20 0.34
SNCA P37840 1/20 0.33
MEN1 O00255 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8149794 0.82 ALDH1A1 (0.48) RBBP9ALDH1A1KMT2AL3MBTL1CYP1A2
SCHEMBL213731 0.80 RBBP9 (0.67) RBBP9ALDH1A1KMT2AL3MBTL1CYP1A2
SCHEMBL2948824 0.78
SCHEMBL2948821 0.78
SCHEMBL13237108 0.78
SCHEMBL213200 0.76 RBBP9 (0.48) RBBP9ALDH1A1KMT2AL3MBTL1CYP1A2
SCHEMBL17183611 0.76
SCHEMBL10785943 0.75 ALDH1A1 (0.46) RBBP9ALDH1A1KMT2AL3MBTL1CYP1A2
SCHEMBL213802 0.74 RBBP9 (0.59) RBBP9ALDH1A1KMT2AL3MBTL1CYP1A2
SCHEMBL213126 0.71 RBBP9 (0.59) RBBP9ALDH1A1KMT2AL3MBTL1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120077941-A1 POLYMERS FUNCTIONALIZED WITH PROTECTED OXIME COMPOUNDS BRIDGESTONE CORPORATION (JP) 2012-03-29 US claimed
US-8088868-B2 oximation of cojugated homopolymers formed by addtion polymerization of conjugated diene monomer in the presence lanthanide copmpounds as polymerization catalysts; polymers used in the manufacture of tires having reduced hysteresis BRIDGESTONE CORPORATION (JP) 2012-01-03 US claimed
US-20080146745-A1 POLYMERS FUNCTIONALIZED WITH PROTECTED OXIME COMPOUNDS BRIDGESTONE CORPORATION (JP) 2008-06-19 US claimed
US-8541509-B2 Polymers functionalized with protected oxime compounds BRIDGESTONE CORPORATION (JP) 2013-09-24 US disclosed
US-20120077941-A1 POLYMERS FUNCTIONALIZED WITH PROTECTED OXIME COMPOUNDS BRIDGESTONE CORPORATION (JP) 2012-03-29 US disclosed
US-8088868-B2 oximation of cojugated homopolymers formed by addtion polymerization of conjugated diene monomer in the presence lanthanide copmpounds as polymerization catalysts; polymers used in the manufacture of tires having reduced hysteresis BRIDGESTONE CORPORATION (JP) 2012-01-03 US disclosed
US-20080146745-A1 POLYMERS FUNCTIONALIZED WITH PROTECTED OXIME COMPOUNDS BRIDGESTONE CORPORATION (JP) 2008-06-19 US disclosed