Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | PPARG | P37231 | 5/20 | 0.57 |
| ▸ | F7 | P08709 | 4/20 | 0.57 |
| ▸ | F3 | P13726 | 4/20 | 0.57 |
| ▸ | PPARD | Q03181 | 4/20 | 0.57 |
| ▸ | PPARA | Q07869 | 4/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.57 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.57 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.57 |
| ▸ | FABP4 | P15090 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.57 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.57 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.57 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20877099 | 1.00 | ALDH1A1 (0.57) | ALDH1A1PPARGF7F3PPARD | |
| SCHEMBL21373200 | 1.00 | ALDH1A1 (0.57) | ALDH1A1PPARGF7F3PPARD | |
| SCHEMBL4758573 | 0.95 | TERT (0.53) | PPARGF7F3PPARDPPARA | |
| SCHEMBL4758572 | 0.95 | TERT (0.53) | PPARGF7F3PPARDPPARA | |
| SCHEMBL16323618 | 0.88 | FASN (0.54) | ALDH1A1PPARGKDM4ETSHRMEN1 | |
| SCHEMBL16323324 | 0.88 | FASN (0.54) | ALDH1A1PPARGKDM4ETSHRMEN1 | |
| SCHEMBL16323325 | 0.88 | FASN (0.54) | ALDH1A1PPARGKDM4ETSHRMEN1 | |
| SCHEMBL16323616 | 0.88 | FASN (0.54) | ALDH1A1PPARGKDM4ETSHRMEN1 | |
| SCHEMBL20835136 | 0.87 | PPARG (0.49) | ALDH1A1PPARGF7F3PPARD | |
| SCHEMBL27277689 | 0.87 | ALDH1A1 (0.56) | ALDH1A1PPARGF7F3PPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3541945-A2 | COMPOSITIONS AND METHODS FOR TARGET NUCLEIC ACID MODIFICATION | Genedit Inc. (US) | 2019-09-25 | — | — | EP | disclosed |