Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 5/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | HTR3A | P46098 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.40 |
| ▸ | DRD1 | P21728 | 2/20 | 0.40 |
| ▸ | DRD3 | P35462 | 2/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2140593 | 0.83 | ALDH1A1 (0.46) | POLBALDH1A1SMN1; SMN2HTTLMNA | |
| SCHEMBL1451666 | 0.81 | POLB (0.54) | POLBALDH1A1SMN1; SMN2HTTLMNA | |
| SCHEMBL2138397 | 0.79 | ALDH1A1 (0.43) | POLBALDH1A1SMN1; SMN2HTTLMNA | |
| SCHEMBL2138385 | 0.79 | ALDH1A1 (0.43) | POLBALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL1451061 | 0.78 | POLB (0.51) | POLBALDH1A1SMN1; SMN2HTTLMNA | |
| SCHEMBL2142156 | 0.77 | ALDH1A1 (0.44) | POLBALDH1A1SMN1; SMN2HTTLMNA | |
| SCHEMBL1451358 | 0.77 | POLB (0.57) | POLBALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL10050523 | 0.77 | POLB (0.57) | POLBALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL19318635 | 0.77 | POLB (0.57) | POLBALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL9605855 | 0.77 | POLB (0.57) | POLBALDH1A1SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8148484-B2 | Poly(bicyclo[2.2.1]hept-5-ene-2-carboxylic acid 2-(tert-butylamino)ethyl ester); Poly(bicyclo[2.2.1]hept-5-ene-2-carboxylic acid 2-(dimethylamino)ethyl ester); used for disinfecting, sterilizing, and preventing biofouling in closed or open industrial-water systems and cooling-water systems | KE KELIT KUNSTSTOFFWERK GESMBH (AT) | 2012-04-03 | — | — | US | disclosed |
| US-20080251460-A1 | Biocidal Polymers | KE KELIT KUNSTSTOFFWERK GESMBH (AT) | 2008-10-16 | — | — | US | disclosed |